Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 2/20 | 0.45 |
| ▸ | KDM5A | P29375 | 2/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | DGKA | P23743 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 6/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | LSS | P48449 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12009424 | 1.00 | DNM1 (0.47) | DNM1LTA4HKDM5ANAAADGKA | |
| SCHEMBL12009427 | 1.00 | DNM1 (0.47) | DNM1LTA4HKDM5ANAAADGKA | |
| SCHEMBL12009426 | 1.00 | DNM1 (0.47) | DNM1LTA4HKDM5ANAAADGKA | |
| SCHEMBL12009421 | 1.00 | DNM1 (0.47) | DNM1LTA4HKDM5ANAAADGKA | |
| SCHEMBL12009425 | 1.00 | DNM1 (0.47) | DNM1LTA4HKDM5ANAAADGKA | |
| SCHEMBL12777800 | 0.98 | LTA4H (0.46) | DNM1LTA4HKDM5ANAAADGKA | |
| SCHEMBL10024729 | 0.94 | DNM1 (0.46) | DNM1LTA4HKDM5ANAAADGKA | |
| SCHEMBL13485241 | 0.88 | MEN1 (0.50) | DNM1LTA4HNAAADGKAACHE | |
| SCHEMBL19629934 | 0.88 | DNM1 (0.64) | DNM1KDM5ANAAADGKAACHE | |
| SCHEMBL7267842 | 0.87 | NAAA (0.55) | DNM1NAAADGKAACHEHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9700627-B2 | Biodegradable poly (beta-amino esters) and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-07-11 | — | — | US | disclosed |
| US-20160022821-A1 | BIODEGRADABLE POLY (BETA-AMINO ESTERS) AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-01-28 | — | — | US | disclosed |
| US-9101666-B2 | Biodegradable poly(beta-amino esters) and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-08-11 | — | — | US | disclosed |
| US-8557231-B2 | Biodegradable poly(beta-amino esters) and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-10-15 | — | — | US | disclosed |
| US-8287849-B2 | Biodegradable poly(beta-amino esters) and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-10-16 | — | — | US | disclosed |
| US-RE43612-E1 | Biodegradable poly(β-amino esters) and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-08-28 | — | — | US | disclosed |
| US-20120065358-A1 | BIODEGRADABLE POLY(BETA-AMINO ESTERS) AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-03-15 | — | — | US | disclosed |
| US-20110257249-A1 | DRUG CARRIERS | NITTO DENKO CORPORATION (JP) | 2011-10-20 | — | — | US | disclosed |
| US-8003621-B2 | Drug carriers | NITTO DENKO CORPORATION (JP) | 2011-08-23 | — | — | US | disclosed |
| US-7943179-B2 | Drug delivery particle; useful in genetic vaccination; eg poly(beta-amino esters) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2011-05-17 | — | — | US | disclosed |
| US-20110059172-A1 | THERAPEUTIC COMPOSITIONS | TZIANABOS ARTHUR | 2011-03-10 | — | — | US | disclosed |
| US-20100036084-A1 | BIODEGRADABLE POLY(BETA-AMINO ESTERS) AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-02-11 | — | — | US | disclosed |
| US-20090105179-A1 | DRUG CARRIERS | NITTO DENKO CORPORATION (JP) | 2009-04-23 | — | — | US | disclosed |
| US-7427394-B2 | Delivering labile agents; buffering effect; transfecting nucleic acids; nontoxic | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110257249-A1 | DRUG CARRIERS | HDGF, FIBP, SLC47A2 | DNM1 2090/4885LTA4H 1922/4885KDM5A 4767/4885 |
| US-20160022821-A1 | BIODEGRADABLE POLY (BETA-AMINO ESTERS) AND USES THEREOF | PARN, PARG, NPEPPS | DNM1 3167/4885LTA4H 3229/4885KDM5A 3491/4885 |
| US-20110059172-A1 | THERAPEUTIC COMPOSITIONS | PHOSPHO1, ACP1, TUBB3 | DNM1 2962/4885LTA4H 2775/4885KDM5A 3282/4885 |
| US-20090105179-A1 | DRUG CARRIERS | HDGF, FIBP, SLC47A2 | DNM1 2090/4885LTA4H 1922/4885KDM5A 4767/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.