SCHEMBL4217318

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10505456	0.82	ALDH1A1 (0.60)	MAPTPLECMEN1KMT2ALMNA
	SCHEMBL4215643	0.82	MAPT (0.52)	MAPTPLECMEN1KMT2ALMNA
	SCHEMBL4211086	0.79	GLO1 (0.51)	MAPTPLECMEN1KMT2ALMNA
	SCHEMBL27716681	0.76	AKR1C3 (0.58)	MEN1KMT2ALMNAAKR1C3AKR1C2
	SCHEMBL4225339	0.76	AKR1C3 (0.73)	MAPTAKR1C3AKR1C2CYP2C9CYP2C19
	SCHEMBL5443633	0.74	KDR (0.60)	MAPTPLECMEN1KMT2ALMNA
	SCHEMBL2293819	0.72	KDR (0.59)	MAPTMEN1KMT2AALDH1A1KDR
	SCHEMBL29775266	0.72	HDAC3 (0.52)	MAPTPLECMEN1KMT2ALMNA
	SCHEMBL13337941	0.72	MEN1 (0.56)	MAPTMEN1KMT2ALMNASLC40A1
	SCHEMBL379216	0.71	GLO1 (0.59)	MAPTMEN1KMT2ALMNASLC40A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.