Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HRAS | P01112 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SCN1A | P35498 | 3/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.35 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | BRS3 | P32247 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2396658 | 0.91 | KMT2A (0.49) | KMT2AHRASPRKCZMEN1NPC1 | |
| SCHEMBL1747972 | 0.81 | KMT2A (0.52) | KMT2ASLC6A3MEN1NPC1SCN1A | |
| SCHEMBL5068457 | 0.81 | KMT2A (0.52) | KMT2ASLC6A3MEN1NPC1SCN1A | |
| SCHEMBL28693105 | 0.74 | BCAT2 (0.46) | KMT2ASLC6A3SLC6A4PRKCZMEN1 | |
| SCHEMBL1854430 | 0.72 | SLC6A3 (0.71) | KMT2ASLC6A3SLC6A4PRKCZMEN1 | |
| SCHEMBL5068496 | 0.71 | KMT2A (0.57) | KMT2AMEN1NPC1RAB9A | |
| SCHEMBL1748263 | 0.71 | KMT2A (0.57) | KMT2AMEN1NPC1RAB9A | |
| SCHEMBL1748271 | 0.71 | NPC1 (0.55) | KMT2ASLC6A3PRKCZMEN1NPC1 | |
| SCHEMBL7441914 | 0.71 | ALDH1A1 (0.61) | KMT2ASLC6A3SLC6A4PRKCZMEN1 | |
| SCHEMBL1747964 | 0.68 | KMT2A (0.49) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090215780-A1 | Preparation and Use of Aryl Alkyl Acid Derivatives for the Treatment of Obesity | BAYER PHARMACEUTICALS CORPORATION (US) | 2009-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215780-A1 | Preparation and Use of Aryl Alkyl Acid Derivatives for the Treatment of Obesity | FABP4, GPR119, LIPC | KMT2A 627/4885HRAS 1073/4885SLC6A3 1440/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.