SCHEMBL4221328

SCHEMBL4221328

C=CCc1cc(Br)ccc1O[Si](C)(C)C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.43
HTT P42858 1/20 0.43
KMT2A Q03164 1/20 0.43
ALOX5 P09917 3/20 0.38
CNR2 P34972 3/20 0.38
GABRA1 P14867 2/20 0.38
GABRB2 P47870 2/20 0.38
MAPK1 P28482 1/20 0.38
ALDH1A1 P00352 2/20 0.37
PPARG P37231 1/20 0.37
PPARD Q03181 1/20 0.37
PPARA Q07869 1/20 0.37
HPGD P15428 1/20 0.36
ELANE P08246 1/20 0.36
PTGDR Q13258 1/20 0.35
PTGDR2 Q9Y5Y4 1/20 0.35
CYP3A4 P08684 1/20 0.35
ALOX15 P16050 1/20 0.35
KDM4E B2RXH2 2/20 0.34
LMNA P02545 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4981069 0.81 GABRA1 (0.55) MEN1HTTKMT2AALOX5CNR2
SCHEMBL16393672 0.81 MAPT (0.40) MEN1KMT2AALOX5CNR2GABRA1
SCHEMBL4215409 0.81 GABRA1 (0.38) ALOX5CNR2GABRA1GABRB2ALDH1A1
SCHEMBL29609173 0.78 ELANE (0.40) MEN1KMT2AALOX5CNR2GABRA1
SCHEMBL16885495 0.78 ELANE (0.40) MEN1KMT2AALOX5CNR2GABRA1
SCHEMBL16885522 0.77 POLB (0.55) MEN1KMT2AALOX5CNR2GABRA1
SCHEMBL8961940 0.76 ALDH1A1 (0.47) ALDH1A1KDM4ELMNATDP1
SCHEMBL29699897 0.76 ALDH1A1 (0.47) ALDH1A1KDM4ELMNATDP1
SCHEMBL16393687 0.75 ELANE (0.35) ALOX5CNR2GABRA1GABRB2MAPK1
SCHEMBL23521372 0.75 ELANE (0.36) ALOX5CNR2GABRA1GABRB2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7557152-B2 Reactive flame retardant and flame-retardant resin processed article FUJI ELECTRIC HOLDINGS CO., LTD. (JP) 2009-07-07 US disclosed
US-20090043032-A1 REACTIVE FLAME RETARDANT AND FLAME-RETARDANT RESIN PROCESSED ARTICLE FUJI ELECTRIC HOLDINGS CO., LTD. (JP) 2009-02-12 US disclosed
EP-1852489-A1 REACTIVE FLAME RETARDANT AND FLAME-RETARDANT RESIN PROCESSED ARTICLE FUJI ELECTRIC HOLDINGS CO., LTD.; (JP) 2007-11-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090043032-A1 REACTIVE FLAME RETARDANT AND FLAME-RETARDANT RESIN PROCESSED ARTICLE F11, PF4, RXRA MEN1 3718/4885HTT 4429/4885KMT2A 3627/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.