Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 3/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4205851 | 0.87 | KCNA5 (0.45) | FAAHCES1SMN1; SMN2EPHX2 | |
| SCHEMBL4213129 | 0.82 | TBXAS1 (0.50) | — | |
| SCHEMBL584902 | 0.70 | LTB4R (0.59) | FAAHGRM2GRM3CES1HDAC3 | |
| SCHEMBL5497372 | 0.69 | KCNA5 (0.48) | SMN1; SMN2LMNAEPHX2 | |
| SCHEMBL31152049 | 0.68 | HDAC3 (0.44) | CES1HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL8085465 | 0.68 | LMNA (0.47) | GRM2GRM3HDAC3MAPK1ADRA1A | |
| SCHEMBL28351862 | 0.67 | POLB (0.53) | FAAHGRM2GRM3CES1HDAC3 | |
| SCHEMBL4221499 | 0.67 | TBXAS1 (0.42) | CES1HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL9716385 | 0.66 | MAPT (0.49) | FAAHGRM2GRM3CES1HDAC3 | |
| SCHEMBL9620173 | 0.66 | MAPT (0.49) | FAAHGRM2GRM3CES1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074093-A2 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2009-07-01 | — | — | EP | claimed |
| WO-2008023336-A2 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2008-02-28 | — | — | WO | claimed |