Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 7/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PTAFR | P25105 | 3/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4205851 | 0.93 | KCNA5 (0.45) | TBXAS1CHRNA7CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4221497 | 0.82 | FAAH (0.38) | — | |
| SCHEMBL8503461 | 0.77 | TBXAS1 (0.59) | TBXAS1CHRNA7TDP1L3MBTL1CYP2A6 | |
| SCHEMBL4212946 | 0.76 | TBXAS1 (0.51) | TBXAS1CHRNA7CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL5497372 | 0.75 | KCNA5 (0.48) | TBXAS1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8046498 | 0.75 | TBXAS1 (0.50) | TBXAS1CHRNA7CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8059121 | 0.72 | FDPS (0.47) | TBXAS1CHRNA7CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8058437 | 0.72 | TBXAS1 (0.49) | TBXAS1CHRNA7CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8058443 | 0.72 | TBXAS1 (0.52) | TBXAS1CHRNA7CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL31152049 | 0.72 | HDAC3 (0.44) | CYP3A4CYP2C9CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074093-A2 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2009-07-01 | — | — | EP | claimed |
| WO-2008023336-A2 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2008-02-28 | — | — | WO | claimed |