Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.52 |
| ▸ | RAB9A | P51151 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 5/20 | 0.49 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4225890 | 0.92 | POLB (0.53) | NPC1RAB9ASMN1; SMN2MAPTLMNA | |
| SCHEMBL4226568 | 0.91 | RAB9A (0.47) | NPC1RAB9ASMN1; SMN2MAPTLMNA | |
| SCHEMBL5071427 | 0.89 | DGAT1 (0.44) | NPC1RAB9ASMN1; SMN2MAPTLMNA | |
| SCHEMBL4221231 | 0.82 | ALDH1A1 (0.47) | NPC1RAB9ASMN1; SMN2MAPTLMNA | |
| SCHEMBL4235449 | 0.78 | ABCB1 (0.45) | — | |
| SCHEMBL13752563 | 0.78 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2MAPTHTT | |
| SCHEMBL13752568 | 0.77 | GAA (0.59) | NPC1RAB9ASMN1; SMN2CA12CA1 | |
| SCHEMBL4226915 | 0.77 | RAB9A (0.50) | NPC1RAB9ASMN1; SMN2MAPTDGAT1 | |
| SCHEMBL3089092 | 0.77 | SMN1; SMN2 (0.59) | NPC1RAB9ASMN1; SMN2MAPTLMNA | |
| SCHEMBL5067991 | 0.77 | RAB9A (0.50) | NPC1RAB9ASMN1; SMN2MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090215780-A1 | Preparation and Use of Aryl Alkyl Acid Derivatives for the Treatment of Obesity | BAYER PHARMACEUTICALS CORPORATION (US) | 2009-08-27 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215780-A1 | Preparation and Use of Aryl Alkyl Acid Derivatives for the Treatment of Obesity | FABP4, GPR119, LIPC | NPC1 187/4885RAB9A 2066/4885SMN1; SMN2 3975/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.