Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.35 |
| ▸ | PPARG | P37231 | 7/20 | 0.35 |
| ▸ | PPARD | Q03181 | 7/20 | 0.35 |
| ▸ | PPARA | Q07869 | 7/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TLR2 | O60603 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | FABP4 | P15090 | 2/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11568571 | 0.70 | LMNA (0.31) | KMT2ASMN1; SMN2 | |
| Hexanoate SCHEMBL2098722 | 0.68 | AKR1B1 (0.59) | KMT2AAKR1B1GPR84PPARGPPARD | |
| SCHEMBL4379010 | 0.68 | AKR1B1 (0.35) | KMT2AAKR1B1GPR84PPARGPPARD | |
| SCHEMBL2100566 | 0.67 | L3MBTL1 (0.50) | KMT2ASMN1; SMN2AKR1B1GPR84PPARG | |
| SCHEMBL1897902 | 0.67 | TLR4 (0.32) | ALDH1A1 | |
| SCHEMBL10794655 | 0.67 | MGLL (0.41) | KMT2ASMN1; SMN2GPR84ALDH1A1HSD17B10 | |
| Palmitic Acid SCHEMBL1815959 | 0.67 | GPR84 (0.61) | KMT2AAKR1B1GPR84PPARGPPARD | |
| Stearic Acid SCHEMBL4612415 | 0.67 | GPR84 (0.61) | KMT2AAKR1B1GPR84PPARGPPARD | |
| Octanoic Acid SCHEMBL5663459 | 0.67 | GPR84 (0.61) | KMT2AAKR1B1GPR84PPARGPPARD | |
| Myristic Acid SCHEMBL3299115 | 0.67 | GPR84 (0.61) | KMT2AAKR1B1GPR84PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7589070-B2 | Surface modification for improving biocompatibility | THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) | 2009-09-15 | — | — | US | disclosed |
| US-20030044408-A1 | Surface modification for improving biocompatibility | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 2003-03-06 | — | — | US | disclosed |
| WO-2002103004-A1 | SURFACE MODIFICATION FOR IMPROVING BIOCOMPATIBILITY | THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) | 2002-12-27 | — | — | WO | disclosed |