Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | PMM2 | O15305 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | MPI | P34949 | 1/20 | 0.37 |
| ▸ | PHOSPHO1 | Q8TCT1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27875767 | 0.98 | S100A4 (0.47) | S100A4TRPV1ERN1LMNAPKM | |
| SCHEMBL16950389 | 0.83 | S100A4 (0.45) | S100A4TRPV1ERN1MAPK1ALDH1A1 | |
| SCHEMBL1561802 | 0.80 | TSHR (0.56) | S100A4TRPV1ERN1LMNAPKM | |
| SCHEMBL24508 | 0.78 | S100A4 (0.56) | S100A4TRPV1ERN1LMNAPKM | |
| SCHEMBL204357 | 0.78 | S100A4 (0.61) | S100A4TRPV1ERN1PKMMAPK1 | |
| SCHEMBL29395434 | 0.78 | S100A4 (0.56) | S100A4TRPV1ERN1LMNAPKM | |
| SCHEMBL3282011 | 0.77 | S100A4 (0.50) | S100A4TRPV1ERN1LMNAPKM | |
| SCHEMBL232696 | 0.77 | TDP1 (0.61) | S100A4LMNAMAPK1ALDH1A1CYP1A2 | |
| SCHEMBL16655574 | 0.75 | S100A4 (0.49) | S100A4TRPV1ERN1LMNAPKM | |
| SCHEMBL405513 | 0.75 | PARP1 (0.53) | S100A4TRPV1ERN1LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230020319-A1 | COMPOSITIONS AND METHODS FOR OPTOCHEMICAL CONTROL OF MTOR SIGNALING AND MTOR-DEPENDENT AUTOPHAGY | THE UNIVERSITY OF HONG KONG (HK) | 2023-01-19 | — | — | US | claimed |
| CN-115531535-A | Compositions and methods for photochemical control of mTOR signaling and mTOR-dependent autophagy | 香港大学 | 2022-12-30 | — | — | CN | claimed |
| EP-3221328-A1 | PHOTOBLOCKED PROBES AND METHODS FOR SEQUENTIAL DETECTION OF NUCLEIC ACIDS | Roche Diagnostics GmbH (DE) | 2017-09-27 | — | — | EP | claimed |
| US-9745618-B2 | Photoblocked probes and methods for sequential detection of nucleic acids | ROCHE MOLECULAR SYSTEMS, INC. (US) | 2017-08-29 | — | — | US | claimed |
| WO-2016079078-A1 | PHOTOBLOCKED PROBES AND METHODS FOR SEQUENTIAL DETECTION OF NUCLEIC ACIDS | ROCHE DIAGNOSTICS GMBH (DE) | 2016-05-26 | — | — | WO | claimed |
| US-20160138092-A1 | PHOTOBLOCKED PROBES AND METHODS FOR SEQUENTIAL DETECTION OF NUCLEIC ACIDS | ROCHE MOLECULAR SYSTEMS, INC. | 2016-05-19 | — | — | US | claimed |
| US-20230020319-A1 | COMPOSITIONS AND METHODS FOR OPTOCHEMICAL CONTROL OF MTOR SIGNALING AND MTOR-DEPENDENT AUTOPHAGY | THE UNIVERSITY OF HONG KONG (HK) | 2023-01-19 | — | — | US | disclosed |
| CN-115531535-A | Compositions and methods for photochemical control of mTOR signaling and mTOR-dependent autophagy | 香港大学 | 2022-12-30 | — | — | CN | disclosed |
| CN-107353217-A | A kind of preparation method of Anthranilate and amides compound | 华南理工大学 | 2017-11-17 | — | — | CN | disclosed |
| EP-3221328-A1 | PHOTOBLOCKED PROBES AND METHODS FOR SEQUENTIAL DETECTION OF NUCLEIC ACIDS | Roche Diagnostics GmbH (DE) | 2017-09-27 | — | — | EP | disclosed |
| US-9745618-B2 | Photoblocked probes and methods for sequential detection of nucleic acids | ROCHE MOLECULAR SYSTEMS, INC. (US) | 2017-08-29 | — | — | US | disclosed |
| WO-2016079078-A1 | PHOTOBLOCKED PROBES AND METHODS FOR SEQUENTIAL DETECTION OF NUCLEIC ACIDS | ROCHE DIAGNOSTICS GMBH (DE) | 2016-05-26 | — | — | WO | disclosed |
| US-20160138092-A1 | PHOTOBLOCKED PROBES AND METHODS FOR SEQUENTIAL DETECTION OF NUCLEIC ACIDS | ROCHE MOLECULAR SYSTEMS, INC. | 2016-05-19 | — | — | US | disclosed |
| CN-1863781-A | 2- (quinoxalin-5-ylsulfonamido) -benzamide compounds as cholecystokinin 2 modulators | JANSSEN PHARMACEUTICA NV (BE) | 2006-11-15 | — | — | CN | disclosed |
| CN-1829704-A | Benzo [1,2,5] thiadiazole compounds as CCK2 modulators | JANSSEN PHARMACEUTICA NV (BE) | 2006-09-06 | — | — | CN | disclosed |
| US-4980096-A | Protective coatings; adhesives | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1990-12-25 | — | — | US | disclosed |
| US-4740600-A | UNBLOCKING WITH ACTINIC RADIATION; PROTECTIVE COATING; THERMOPLASTIC RESIN MIXTURES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1988-04-26 | — | — | US | disclosed |
| US-4599273-A | PROTECTIVE COATINGS, PRESSURE SENSITIVE ADHESIVES | MINNESOTA MINING AND MANUFACTURING CO. (US) | 1986-07-08 | — | — | US | disclosed |
| US-4478967-A | Photolabile blocked surfactants and compositions containing the same | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1984-10-23 | — | — | US | disclosed |
| EP-0046083-A2 | Photolabile blocked surfactants and compositions containing the same | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1982-02-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230020319-A1 | COMPOSITIONS AND METHODS FOR OPTOCHEMICAL CONTROL OF MTOR SIGNALING AND MTOR-DEPENDENT AUTOPHAGY | MTOR, RICTOR, SQSTM1 | S100A4 4087/4885TRPV1 3325/4885ERN1 2392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.