Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 4/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1871681 | 0.85 | L3MBTL1 (0.40) | KLKB1ALDH1A1LMNANPC1L3MBTL1 | |
| SCHEMBL18330041 | 0.85 | KLKB1 (0.39) | KLKB1ALDH1A1LMNANPC1L3MBTL1 | |
| SCHEMBL26133925 | 0.84 | L3MBTL1 (0.40) | KLKB1ALDH1A1LMNANPC1L3MBTL1 | |
| SCHEMBL439674 | 0.81 | KLKB1 (0.35) | KLKB1ALDH1A1LMNASMN1; SMN2POLB | |
| SCHEMBL16892760 | 0.80 | TSHR (0.41) | KLKB1ALDH1A1LMNANPC1KDM4E | |
| Hydrochloric Acid SCHEMBL38654637 | 0.80 | KLKB1 (0.34) | KLKB1ALDH1A1LMNASMN1; SMN2POLB | |
| SCHEMBL21724115 | 0.79 | KLKB1 (0.35) | KLKB1 | |
| SCHEMBL8932291 | 0.76 | CYP11B1 (0.33) | KLKB1LMNAPOLBMEN1KMT2A | |
| SCHEMBL22976065 | 0.76 | ALDH1A1 (0.51) | ALDH1A1LMNANPC1L3MBTL1KDM4E | |
| SCHEMBL5212788 | 0.74 | LMNA (0.41) | KLKB1ALDH1A1LMNANPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090069398-A1 | Pyrazolyl Carboxamides | BAYER CROPSCIENCE AG (DE) | 2009-03-12 | — | — | US | disclosed |
| US-20090069398-A1 | Pyrazolyl Carboxamides | BAYER CROPSCIENCE AG (DE) | 2009-03-12 | — | — | US | disclosed |
| US-20090069398-A1 | Pyrazolyl Carboxamides | BAYER CROPSCIENCE AG (DE) | 2009-03-12 | — | — | US | disclosed |
| EP-1965642-A2 | PYRAZOLYL CARBOXAMIDES | Bayer CropScience AG (DE) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007068370-A2 | PYRAZOLYL CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2007-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069398-A1 | Pyrazolyl Carboxamides | MRPL21, AADAC, PGLS | KLKB1 4669/4885ALDH1A1 709/4885LMNA 3751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.