SCHEMBL423258

SCHEMBL423258

CCCCCC(CC)COc1ccc(C=CC(=O)O)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.59
THRB P10828 1/20 0.48
ATM Q13315 1/20 0.48
ABCG2 Q9UNQ0 1/20 0.46
LMNA P02545 1/20 0.46
PRSS1 P07477 1/20 0.45
PRSS2 P07478 1/20 0.45
PRSS3 P35030 1/20 0.45
NPC1 O15118 3/20 0.45
RAB9A P51151 3/20 0.45
KDM4E B2RXH2 2/20 0.45
ALDH1A1 P00352 2/20 0.45
HPGD P15428 1/20 0.45
CASP3 P42574 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
SENP8 Q96LD8 1/20 0.45
SENP7 Q9BQF6 1/20 0.45
SENP6 Q9GZR1 1/20 0.45
POLB P06746 1/20 0.44
TAS1R3 Q7RTX0 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2038409 0.96 TDP1 (0.63) TDP1THRBATMABCG2LMNA
SCHEMBL2038405 0.96 TDP1 (0.63) TDP1THRBATMABCG2LMNA
SCHEMBL9629362 0.87 TDP1 (0.46) TDP1THRBATMABCG2NPC1
SCHEMBL8081146 0.86 THRB (0.49) TDP1THRBATMABCG2NPC1
SCHEMBL29090825 0.86 TDP1 (0.57) TDP1THRBATMABCG2LMNA
SCHEMBL8081148 0.86 THRB (0.49) TDP1THRBATMABCG2NPC1
SCHEMBL17212259 0.86 TDP1 (0.63) TDP1ABCG2LMNAPRSS1PRSS2
SCHEMBL28415884 0.85 ABCG2 (0.52) TDP1THRBATMABCG2POLB
SCHEMBL1391294 0.85 TDP1 (0.56) TDP1THRBATMABCG2LMNA
SCHEMBL7181303 0.84 TDP1 (0.53) TDP1ABCG2LMNAPOLBPLA2G4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 744 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4748367-A2 SUNSCREEN COMPOSITION DSM IP Assets B.V. (NL) 2026-05-27 EP claimed
EP-4568640-B1 SUNSCREEN COMPOSITION DSM IP ASSETS BV (NL) 2026-05-13 EP claimed
US-12622861-B2 Stable wash composition CONOPCO, INC. (US) 2026-05-12 US claimed
US-12582588-B2 Solid cosmetic composition for blocking ultraviolet radiation having water resistance and cleansing properties LG HOUSEHOLD & HEALTH CARE LTD. (KR) 2026-03-24 US claimed
US-12502348-B2 Ultraviolet blocking cosmetic composition in chromatic emulsion state LG HOUSEHOLD & HEALTH CARE LTD. (KR) 2025-12-23 US claimed
US-12409117-B2 Wash composition substantially free of oil CONOPCO, INC. (US) 2025-09-09 US claimed
US-20250205130-A1 Hydratable Concentrate Composition and Sulfate free Wash Composition CONOPCO, INC., D/B/A UNILEVER (US) 2025-06-26 US claimed
EP-4568640-A1 SUNSCREEN COMPOSITION DSM IP Assets B.V. (NL) 2025-06-18 EP claimed
EP-4546956-A1 HOUSING, ELECTRONIC DEVICE COMPRISING HOUSING, AND METHOD FOR MANUFACTURING HOUSING Samsung Electronics Co., Ltd. (KR) 2025-04-30 EP claimed
WO-2025078919-A1 TOPICAL COMPOSITION Exalya S.r.l. (IT) 2025-04-17 WO claimed
WO-2007073838-A1 COSMETIC W/O EMULSIONS WITH ORGANIC SUNSCREENS AND CONJUGATED LINOLEIC ACID UNILEVER PLC (GB) 2007-07-05 WO claimed
US-7172754-B1 Cosmetic emulsions with sunscreens and conjugated linoleic acid CONOPCO, INC. (US) 2007-02-06 US claimed
WO-2006112865-A1 PERSONAL CARE COMPOSITIONS COMPRISING SILICONE RESINS WITH ENHANCED PROPERTIES, METHOD OF MANUFACTURE, AND METHOD OF USE THEREOF GENERAL ELECTRIC COMPANY (US) 2006-10-26 WO claimed
EP-1108419-B1 Cosmetic composition and methods of use AVON PROD INC (US) 2005-12-28 EP claimed
US-20050249690-A1 Personal care compositions with enhanced properties, method of manufacture, and method of use thereof MOMENTIVE PERFORMANCE MATERIALS INC. 2005-11-10 US claimed
US-20050249689-A1 Personal care compositions with enhanced properties, method of manufacture, and method of use thereof MOMENTIVE PERFORMANCE MATERIALS INC. 2005-11-10 US claimed
WO-2004062635-A1 COMPOSITIONS FOR SKIN LIGHTENING COMPRISING BIS-PANTOYL-CYSTAMINE DSM IP ASSETS B.V. (NL) 2004-07-29 WO claimed
US-6521668-B2 For protection of keratinous tissue against environmental aggressors such as smoke, smog and UV radiation; contain as essential antioxidants hesperetin, tetrahydrocurcumin, tetrahydrodemethoxycurcumin AVON PRODUCTS, INC. 2003-02-18 US claimed
US-5989529-A Substantive topical composition SCHERING-PLOUGH HEALTHCARE PRODUCTS, INC. (US) 1999-11-23 US claimed
US-5547659-A OIL IN WATER SUNSCREEN EMULSION COMPRISING OCTOCRYLENE, ETHYLHEXYL-P-METHOXY CINNAMATE, TITANIUM DIOXIDE, UNSATURATED ESTER AND UNSATURATED AMIDE POLYMERS, WAXES RICHARDSON-VICKS INC. (US) 1996-08-20 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12622861-B2 Stable wash composition ALG1, IL4, CUTA TDP1 3503/4885THRB 3002/4885ATM 1154/4885
US-12582588-B2 Solid cosmetic composition for blocking ultraviolet radiation having water resistance and cleansing properties CUTA, TRPA1, ERCC5 TDP1 1304/4885THRB 1302/4885ATM 11/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.