Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 2/20 | 0.55 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.55 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HRH2 | P25021 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ESRRG | P62508 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2181725 | 0.78 | APAF1 (0.46) | HRH3KCNH2NPSR1ESRRGPOLB | |
| SCHEMBL10891769 | 0.78 | CNR1 (0.59) | HRH3MCHR1CHRM1HTR2AKCNH2 | |
| SCHEMBL23671492 | 0.78 | SIGMAR1 (0.56) | KDM4EALDH1A1ESRRGGAA | |
| SCHEMBL4804050 | 0.78 | ALDH1A1 (0.50) | HRH3MCHR1ALDH1A1NPSR1ESRRG | |
| SCHEMBL14175271 | 0.78 | MAPT (0.55) | HRH3HRH1KDM4EALDH1A1HPGD | |
| SCHEMBL2010540 | 0.78 | HRH3 (0.40) | CACNA1BCACNA1HHRH3HRH2HRH1 | |
| SCHEMBL17120729 | 0.78 | BACE1 (0.52) | MCHR1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8673780 | 0.78 | POLB (0.59) | HRH3ALDH1A1NPSR1ESRRGPOLB | |
| SCHEMBL7049256 | 0.76 | DPP7 (0.64) | CACNA1BCACNA1HHRH3HRH2HRH1 | |
| Hydrochloric Acid SCHEMBL11093613 | 0.76 | POLB (0.58) | HRH3ALDH1A1ESRRGPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090233910-A1 | Npy antagonists, preparation and uses | CEREP (FR) | 2009-09-17 | — | — | US | disclosed |
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233910-A1 | Npy antagonists, preparation and uses | NPY1R, NPY5R, NPY2R | CACNA1B 774/4885CACNA1H 1252/4885HRH3 210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.