Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.51 |
| ▸ | APAF1 | O14727 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3956042 | 0.82 | RAB9A (0.57) | SMN1; SMN2MAPTMEN1KMT2AMAPKAPK2 | |
| SCHEMBL4245782 | 0.79 | SMN1; SMN2 (0.54) | SMN1; SMN2MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL2346560 | 0.73 | RARA (0.66) | SMN1; SMN2MAPTMEN1KMT2AMAPK1 | |
| SCHEMBL2913173 | 0.73 | PKM (0.65) | SMN1; SMN2MAPTMEN1KMT2AMAPK1 | |
| SCHEMBL4235980 | 0.72 | MAPT (0.52) | SMN1; SMN2MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL2352480 | 0.71 | PKM (0.70) | SMN1; SMN2MAPTMEN1KMT2AMAPK1 | |
| SCHEMBL2345369 | 0.71 | RARB (0.66) | SMN1; SMN2MAPTMAPK1NPC1RAB9A | |
| SCHEMBL2342385 | 0.71 | PKM (0.61) | SMN1; SMN2MAPTMEN1KMT2AMAPK1 | |
| SCHEMBL12700228 | 0.71 | MEN1 (0.64) | SMN1; SMN2MAPTMEN1KMT2AMAPK1 | |
| SCHEMBL4240335 | 0.71 | MAPT (0.55) | SMN1; SMN2MAPTL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009034390-A1 | HETEROCYCLIC DERIVATIVES AND THEIR USE IN TREATING HEPATITIS C | ARROW THERAPEUTICS LIMITED (GB) | 2009-03-19 | — | — | WO | disclosed |