SCHEMBL4237428

SCHEMBL4237428

CCOC(=O)CC(=O)NC(CC(=O)OC)Cc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MMEL1 Q495T6 3/20 0.48
MME P08473 5/20 0.48
MMP8 P22894 1/20 0.46
TP53 P04637 1/20 0.44
HPGD P15428 1/20 0.44
ABCB1 P08183 1/20 0.44
PPID Q08752 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13744623 0.90 MME (0.54) MMEL1MMEHPGDABCB1
SCHEMBL2636079 0.84 ALDH1A1 (0.51) MMEL1MMEMMP8TP53HPGD
SCHEMBL13825642 0.83 ALDH1A1 (0.52) MMEHPGD
SCHEMBL13744224 0.82 MME (0.48) MMEL1MME
SCHEMBL13825640 0.81 MME (0.50) MMEL1MMEHPGD
SCHEMBL14959388 0.81 MMEL1 (0.59) MMEL1MME
SCHEMBL14611003 0.80 CTRB1 (0.53) ABCB1
SCHEMBL14392786 0.80 CTRB1 (0.53) ABCB1
SCHEMBL6222640 0.80 MMEL1 (0.45) MMEL1PPID
SCHEMBL8141223 0.78 ALDH1A1 (0.53) MMP8TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090203694-A1 INHIBITORS OF UNDECAPRENYL PYROPHOSPHATE SYNTHASE HURLEY TIMOTHY BRIAN 2009-08-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090203694-A1 INHIBITORS OF UNDECAPRENYL PYROPHOSPHATE SYNTHASE FDPS, UMPS, GGPS1 MMEL1 1247/4885MME 1183/4885MMP8 3626/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.