Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4244284 | 1.00 | TTR (0.46) | TTRMAPTALDH1A1CYP3A4HPGD | |
| SCHEMBL13918063 | 0.91 | TTR (0.49) | TTRMAPTALDH1A1MEN1LMNA | |
| SCHEMBL4237599 | 0.86 | MAPT (0.46) | MAPTALDH1A1CYP3A4HPGDKMT2A | |
| SCHEMBL4237341 | 0.86 | MAPT (0.46) | MAPTALDH1A1CYP3A4HPGDKMT2A | |
| SCHEMBL13918064 | 0.83 | HDAC1 (0.45) | MAPTALDH1A1CYP3A4HPGDKMT2A | |
| SCHEMBL13918058 | 0.82 | ALDH1A1 (0.39) | MAPTALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL4238188 | 0.79 | HDAC1 (0.47) | MAPTCYP3A4MEN1LMNAKMT2A | |
| SCHEMBL13918060 | 0.79 | RARA (0.39) | MAPTALDH1A1CYP3A4HPGDNFE2L2 | |
| SCHEMBL4402172 | 0.79 | NFE2L2 (0.59) | NFE2L2 | |
| SCHEMBL4237469 | 0.79 | TRPM8 (0.51) | MAPTALDH1A1CYP3A4HPGDNFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7507509-B2 | Electrophotographic photoreceptor, and image forming method, image forming apparatus and process cartridge using the electrophotographic photoreceptor | RICOH COMPANY, LTD. (JP) | 2009-03-24 | — | — | US | disclosed |
| US-7507509-B2 | Electrophotographic photoreceptor, and image forming method, image forming apparatus and process cartridge using the electrophotographic photoreceptor | RICOH COMPANY, LTD. (JP) | 2009-03-24 | — | — | US | disclosed |
| US-20060078809-A1 | Electrophotographic photoreceptor, and image forming method, image forming apparatus and process cartridge using the electrophotographic photoreceptor | RICOH COMPANY, LTD. (JP) | 2006-04-13 | — | — | US | disclosed |