SCHEMBL4239389

SCHEMBL4239389

COCc1ccccc1C(O)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FABP4 P15090 2/20 0.48
FABP5 Q01469 2/20 0.48
LMNA P02545 2/20 0.42
MAPK1 P28482 1/20 0.42
FFAR1 O14842 1/20 0.39
NPSR1 Q6W5P4 2/20 0.37
POLB P06746 1/20 0.37
HTT P42858 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
PRMT5 O14744 1/20 0.37
KDM4E B2RXH2 1/20 0.36
PRKCE Q02156 1/20 0.36
P2RX3 P56373 1/20 0.36
TSHR P16473 1/20 0.36
KMT2A Q03164 1/20 0.35
BLM P54132 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8209562 0.83 ALDH1A1 (0.51) FABP4FABP5LMNAMAPK1L3MBTL1
SCHEMBL1190785 0.82 PRMT5 (0.38) FABP4FABP5LMNAFFAR1NPSR1
SCHEMBL1190584 0.82 CASP1 (0.43) LMNAPOLBL3MBTL1KDM4ETSHR
SCHEMBL3266290 0.82 LMNA (0.48) FABP4FABP5LMNAMAPK1POLB
SCHEMBL5570575 0.82 LMNA (0.48) FABP4FABP5LMNAMAPK1POLB
SCHEMBL16458088 0.81 FABP4 (0.53) FABP4FABP5LMNAMAPK1FFAR1
SCHEMBL15375391 0.80 FABP4 (0.59) FABP4FABP5LMNAMAPK1FFAR1
SCHEMBL15375432 0.79 FABP4 (0.57) FABP4FABP5LMNAKMT2A
SCHEMBL15375328 0.79 FABP4 (0.57) FABP4FABP5L3MBTL1TSHRKMT2A
SCHEMBL15375447 0.79 FABP4 (0.57) FABP4FABP5NPSR1POLBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2138578-A1 REDUCTASE, GENE THEREOF AND METHOD OF USING THE SAME Sumitomo Chemical Company, Limited (JP) 2009-12-30 EP disclosed
EP-2138579-A1 REDUCTASE, GENE THEREOF AND METHOD OF USING THE SAME Sumitomo Chemical Company, Limited (JP) 2009-12-30 EP disclosed