SCHEMBL4240914

SCHEMBL4240914

NC(=CC(=O)O)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.54
TSHR P16473 2/20 0.54
CYP2C19 P33261 2/20 0.54
CYP3A4 P08684 2/20 0.54
MAPT P10636 2/20 0.54
BLM P54132 2/20 0.54
POLB P06746 1/20 0.54
PARP1 P09874 1/20 0.54
RECQL P46063 1/20 0.54
PMP22 Q01453 1/20 0.54
HSD17B10 Q99714 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
CA12 O43570 2/20 0.48
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
CA9 Q16790 2/20 0.48
CA3 P07451 1/20 0.48
CA4 P22748 1/20 0.48
CA6 P23280 1/20 0.48
CA5A P35218 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28337358 1.00 TDP1 (0.54) TDP1TSHRCYP2C19CYP3A4MAPT
SCHEMBL4240912 1.00 TDP1 (0.54) TDP1TSHRCYP2C19CYP3A4MAPT
SCHEMBL11858226 0.86 TDP1 (0.54) TDP1TSHRCYP2C19CYP3A4MAPT
SCHEMBL11858221 0.86 TDP1 (0.54) TDP1TSHRCYP2C19CYP3A4MAPT
SCHEMBL3140459 0.84 NFE2L2 (0.61) TDP1TSHRCYP2C19CYP3A4MAPT
SCHEMBL29089429 0.84 NFE2L2 (0.61) TDP1TSHRCYP2C19CYP3A4MAPT
SCHEMBL3140451 0.84 NFE2L2 (0.61) TDP1TSHRCYP2C19CYP3A4MAPT
SCHEMBL2675175 0.82 TDP1 (0.50) TDP1TSHRCYP2C19CYP3A4MAPT
SCHEMBL2675176 0.82 TDP1 (0.50) TDP1TSHRCYP2C19CYP3A4MAPT
SCHEMBL11115897 0.82 NFE2L2 (0.59) TDP1TSHRCYP2C19CYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106983741-A Application of the cyanoacrylate compound in treatment people and animals' fungal infection disease 南京农业大学 2017-07-28 CN claimed
CN-119731255-A Use of additives for improving the processing of polyethylene 巴斯夫欧洲公司 2025-03-28 CN disclosed
CN-104488869-B A kind of bactericidal composition of the ethyl phenylacrylate of 2 cyano group, 3 amino 3 and Osthole 江苏省农药研究所股份有限公司 2017-10-31 CN disclosed
CN-106983741-A Application of the cyanoacrylate compound in treatment people and animals' fungal infection disease 南京农业大学 2017-07-28 CN disclosed
US-20090203694-A1 INHIBITORS OF UNDECAPRENYL PYROPHOSPHATE SYNTHASE HURLEY TIMOTHY BRIAN 2009-08-13 US disclosed
CN-101475504-A 2-acetyl-3-amino-3-aryl-acrylic acid esters and preparation thereof UNIV SOOCHOW (CN) 2009-07-08 CN disclosed
US-5698577-A ANTIBIOTICS HOFFMANN-LA ROCHE INC. (US) 1997-12-16 US disclosed
EP-0212972-A2 Bioconversion process ALLELIX INC. (CA) 1987-03-04 EP disclosed
US-4336389-A 2-Substituted-4-aryl-5-thiazolecarboxylic acids and their derivatives as safening agents MONSANTO COMPANY (US) 1982-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090203694-A1 INHIBITORS OF UNDECAPRENYL PYROPHOSPHATE SYNTHASE FDPS, UMPS, GGPS1 TDP1 1147/4885TSHR 4769/4885CYP2C19 3325/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.