Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4250554 | 0.85 | TDP1 (0.43) | TP53CYP3A4TDP1CALM1TSHR | |
| SCHEMBL28156449 | 0.83 | LTA4H (0.52) | TP53TDP1ALDH1A1IDO1SMN1; SMN2 | |
| SCHEMBL231466 | 0.83 | CYP3A4 (0.45) | TP53CYP3A4TDP1CALM1TSHR | |
| SCHEMBL4251209 | 0.83 | TP53 (0.41) | TP53CYP3A4TDP1CALM1TSHR | |
| SCHEMBL14609301 | 0.81 | TDP1 (0.39) | TP53CYP3A4TDP1CALM1TSHR | |
| SCHEMBL9883762 | 0.81 | TDP1 (0.39) | TP53CYP3A4TDP1CALM1TSHR | |
| SCHEMBL4257325 | 0.80 | CYP3A4 (0.43) | TP53CYP3A4TDP1CALM1TSHR | |
| SCHEMBL11551492 | 0.80 | CYP3A4 (0.43) | TP53CYP3A4TDP1CALM1TSHR | |
| SCHEMBL15660615 | 0.80 | CALM1 (0.43) | TP53CYP3A4TDP1CALM1TSHR | |
| SCHEMBL5588513 | 0.80 | CYP3A4 (0.43) | TP53CYP3A4TDP1CALM1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1876193-B1 | PROCESS FOR PRODUCING POLYOXYMETHYLENE COPOLYMER | MITSUBISHI GAS CHEMICAL CO (JP) | 2013-12-25 | — | — | EP | disclosed |
| US-7897672-B2 | Process for producing polyoxymethylene copolymer | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2011-03-01 | — | — | US | disclosed |
| US-20090062503-A1 | Process for Producing Polyoxymethylene Copolymer | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2009-03-05 | — | — | US | disclosed |
| EP-1876193-A1 | PROCESS FOR PRODUCING POLYOXYMETHYLENE COPOLYMER | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2008-01-09 | — | — | EP | disclosed |
| US-7309799-B2 | Methods for the synthesis of milnacipran and congeners thereof | COLLEGIUM PHARMACEUTICAL, INC. (US) | 2007-12-18 | — | — | US | disclosed |
| US-20050282898-A1 | Methods for the synthesis of milnacipran and congeners thereof | COLLEGIUM PHARMACEUTICAL (US) | 2005-12-22 | — | — | US | disclosed |
| WO-2005118564-A2 | METHODS FOR THE SYNTHESIS OF MILNACIPRAN AND CONGENERS THEREOF | COLLEGIUM PHARMACEUTICAL, INC. (US) | 2005-12-15 | — | — | WO | disclosed |
| US-20030072716-A1 | Renewable, carbohydrate based CO2-philes | POOVATHINTHODIYIL RAVEENDRAN (US) | 2003-04-17 | — | — | US | disclosed |
| WO-2003000192-A2 | RENEWABLE, CARBOHYDRATE BASED CO2-PHILES | POOVATHINTHODIYIL RAVEENDRAN (US) | 2003-01-03 | — | — | WO | disclosed |
| US-5817590-A | METALLOCENE, IONIZING IONIC COMPOUND, ORGANOALUMINUM COMPOUND, LEWIS BASE | TOSOH CORPORATION (JP) | 1998-10-06 | — | — | US | disclosed |
| US-5576259-A | POLYMERIZATION CATALYST INCLUDING METALLOCENE COMPOUND, IONIC COMPOUND, ORGANOALUMINUM COMPOUND, AND LEWIS BASE | TOSOH CORPORATION (JP) | 1996-11-19 | — | — | US | disclosed |
| EP-0648786-A1 | Process for producing alpha-olefin polymer | Tosoh Corporation (JP) | 1995-04-19 | — | — | EP | disclosed |
| EP-0619326-A1 | Olefin polymerization catalyst and olefin polymerisation process | TOSOH CORPORATION (JP) | 1994-10-12 | — | — | EP | disclosed |
| US-4342680-A | WITH AN AMINE SUBSTITUTED TRIAZINE, A PHENOL, AND AN ALKALI METAL | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1982-08-03 | — | — | US | disclosed |
| US-4339569-A | BULK POLYMERIZATION, BORON TRIFLUORIDE CATALYSTS | MITSUBISHI GAS CHEMICAL CO., INC. (JP) | 1982-07-13 | — | — | US | disclosed |
| EP-0034935-A1 | Titanium trichloride catalyst and process for production of alpha-olefin polymers | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-09-02 | — | — | EP | disclosed |
| US-4187385-A | TITANIUM COMPONENT COPULVERIZED WITH ORGANOALUMINUM COMPOUND AND ETHYLENE OR A-OLEFINS, PARTICLE SIZE | MITSUI TOATSU CHEMICAL, INC. (JP) | 1980-02-05 | — | — | US | disclosed |
| US-4125540-A | WITH ORGANO-PHOSPHORUS COMPOUNDS | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1978-11-14 | — | — | US | disclosed |
| US-4087411-A | TRIOXANE, BORON FLUORIDE-TYPE CATALYST | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JA) | 1978-05-02 | — | — | US | disclosed |
| US-4028481-A | ACTIVATED TITANIUM TRICHLORIDE AND AN ORGANOALUMINUM COMPOUND | MITSUI TOATSU CHEMICALS, INCORPORATED (JA) | 1977-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030072716-A1 | Renewable, carbohydrate based CO2-philes | CA2, GYS2, CA12 | TP53 1500/4885CYP3A4 1475/4885TDP1 4386/4885 |
| US-20050282898-A1 | Methods for the synthesis of milnacipran and congeners thereof | ALDH3A1, DHPS, COASY | TP53 4821/4885CYP3A4 77/4885TDP1 2760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.