Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.42 |
| ▸ | FAAH | O00519 | 8/20 | 0.41 |
| ▸ | MGLL | Q99685 | 8/20 | 0.41 |
| ▸ | GAA | P10253 | 5/20 | 0.36 |
| ▸ | MGAM | O43451 | 4/20 | 0.36 |
| ▸ | AMY1A | P0DUB6 | 4/20 | 0.36 |
| ▸ | SI | P14410 | 4/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL425750 | 0.88 | TRPV1 (0.38) | FAAHMGLLGAAMGAMAMY1A | |
| SCHEMBL425936 | 0.85 | KCNMA1 (0.39) | KCNMA1FAAHMGLLGAAMGAM | |
| SCHEMBL424701 | 0.85 | F12 (0.42) | FAAHMGLLGAAMGAMAMY1A | |
| SCHEMBL425578 | 0.85 | FAAH (0.47) | KCNMA1FAAHMGLLGAAMGAM | |
| SCHEMBL444875 | 0.84 | HCAR3 (0.40) | FAAHMGLLGAAMGAMAMY1A | |
| SCHEMBL427663 | 0.83 | FAAH (0.36) | KCNMA1FAAHMGLLGAAMGAM | |
| SCHEMBL425972 | 0.83 | KDM4E (0.36) | KCNMA1MGLLGAAHPGDALDH1A1 | |
| SCHEMBL424905 | 0.82 | RAB9A (0.48) | FAAHMGLLHPGDALDH1A1HSD17B10 | |
| SCHEMBL7899384 | 0.81 | GAA (0.32) | KCNMA1FAAHMGLLGAAMGAM | |
| SCHEMBL425919 | 0.81 | HDAC3 (0.43) | FAAHMGLLGAAMGAMAMY1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9353082-B2 | Pharmaceutical compounds | BIAL—PORTELA & CA, S.A. (PT) | 2016-05-31 | — | — | US | disclosed |
| US-9353082-B2 | Pharmaceutical compounds | BIAL—PORTELA & CA, S.A. (PT) | 2016-05-31 | — | — | US | disclosed |
| US-20120065191-A1 | PHARMACEUTICAL COMPOUNDS | BIAL - PORTELA & Cª, S.A. (PT) | 2012-03-15 | — | — | US | disclosed |
| US-20120065191-A1 | PHARMACEUTICAL COMPOUNDS | BIAL - PORTELA & Cª, S.A. (PT) | 2012-03-15 | — | — | US | disclosed |
| WO-2010074588-A2 | PHARMACEUTICAL COMPOUNDS | BIAL - PORTELA & Cª, S.A. (PT) | 2010-07-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065191-A1 | PHARMACEUTICAL COMPOUNDS | FAAH, FAAH2, ASAH1 | KCNMA1 3175/4885FAAH 1/4885MGLL 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.