Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.55 |
| ▸ | CDYL2 | Q8N8U2 | 8/20 | 0.52 |
| ▸ | CDYL | Q9Y232 | 8/20 | 0.52 |
| ▸ | CBX7 | O95931 | 7/20 | 0.52 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 6/20 | 0.52 |
| ▸ | CD74 | P04233 | 2/20 | 0.48 |
| ▸ | MIF | P14174 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4067603 | 0.89 | KMO (0.46) | KMOCDYL2CDYLCBX7CDY1; CDY1B | |
| SCHEMBL29957877 | 0.73 | KMO (0.76) | KMOCDYL2CDYLCBX7CDY1; CDY1B | |
| SCHEMBL2950965 | 0.73 | KMO (0.76) | KMOCDYL2CDYLCBX7CDY1; CDY1B | |
| SCHEMBL29958210 | 0.72 | CDYL2 (0.69) | KMOCDYL2CDYLCBX7CDY1; CDY1B | |
| SCHEMBL27033393 | 0.72 | CDYL2 (0.69) | KMOCDYL2CDYLCBX7CDY1; CDY1B | |
| SCHEMBL14615630 | 0.72 | KMO (0.67) | KMOCDYL2CDYLCBX7CDY1; CDY1B | |
| SCHEMBL29999740 | 0.71 | KDM4E (0.47) | KMOCDYL2CDYLCBX7CDY1; CDY1B | |
| SCHEMBL2953262 | 0.70 | KMO (0.60) | KMOCDYL2CDYLCBX7CDY1; CDY1B | |
| SCHEMBL8463444 | 0.70 | KDM4E (0.44) | ALDH1A1KDM4EHPGDSMN1; SMN2NPC1 | |
| SCHEMBL13099996 | 0.69 | CDYL2 (0.64) | KMOCDYL2CDYLCBX7CDY1; CDY1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049118-A1 | MORPHOLINYL AND PYRROLIDINYL ANALOGS | SmithKline Beecham Corporation (US) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008011551-A1 | MORPHOLINYL AND PYRROLIDINYL ANALOGS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-01-24 | — | — | WO | disclosed |