SCHEMBL29999740

SCHEMBL29999740

COc1ccc2c(c1)oc(=O)n2OC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.47
ALDH1A1 P00352 5/20 0.47
HPGD P15428 3/20 0.47
HSD17B10 Q99714 2/20 0.47
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
CA3 P07451 1/20 0.47
AKR1B1 P15121 1/20 0.47
CA4 P22748 1/20 0.47
CA6 P23280 1/20 0.47
CA5A P35218 1/20 0.47
CA7 P43166 1/20 0.47
CA9 Q16790 1/20 0.47
CA14 Q9ULX7 1/20 0.47
NPC1 O15118 3/20 0.45
MAPT P10636 3/20 0.45
RAB9A P51151 3/20 0.45
POLB P06746 2/20 0.45
STAT1 P42224 1/20 0.45
CASP3 P42574 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4067603 0.83 KMO (0.46) KDM4EALDH1A1HPGDHSD17B10CA12
SCHEMBL8296662 0.81 L3MBTL1 (0.60) KDM4EALDH1A1HPGDHSD17B10CA12
SCHEMBL8798706 0.75 KDM4E (0.43) KDM4EALDH1A1HPGDHSD17B10CA12
SCHEMBL8798927 0.74 MET (0.57) ALDH1A1HPGDMAPTPOLBSMN1; SMN2
SCHEMBL14199043 0.74 POLB (0.52) ALDH1A1HPGDMAPTPOLBSMN1; SMN2
SCHEMBL4242148 0.73 KMO (0.61) POLBSMN1; SMN2KMOMETLMNA
Hydrochloric Acid SCHEMBL9157992 0.73 MET (0.56) ALDH1A1HPGDMAPTPOLBSMN1; SMN2
SCHEMBL805919 0.73 ADRA1D (0.52) KDM4EALDH1A1HPGDHSD17B10CA12
SCHEMBL2149713 0.72 MAPT (0.56) ALDH1A1HPGDMAPTRAB9APOLB
SCHEMBL4413088 0.72 HPGD (0.59) HPGDPOLBSMN1; SMN2KMOMET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117794534-A Compositions for modulating cortisol homeostasis and improving sleep quality and methods of use and preparation thereof 尤尼根公司 2024-03-29 CN claimed
US-20240299464-A1 BOTANICAL COMPOUNDS, METHODS, AND PROCEDURES FOR MEDICINAL TREATMENT RELATED TO IMMUNOINFLAMMATION, NEUROINFLAMMATION, DEPRESSION, MEMORY, FOCUS, AND NERVE DEGENERATION NGUYEN MINH H (US) 2024-09-12 US disclosed
WO-2024173722-A2 BOTANICAL COMPOUNDS, METHODS, AND PROCEDURES FOR MEDICINAL TREATMENT RELATED TO IMMUNOINFLAMMATION, NEUROINFLAMMATION, DEPRESSION, MEMORY, FOCUS, AND NERVE DEGENERATION NGUYEN MINH H (US) 2024-08-22 WO disclosed
EP-4346810-A1 COMPOSITIONS FOR REGULATING HOMEOSTASIS OF CORTISOL AND IMPROVING SLEEP QUALITY AND METHODS OF USE AND PRODUCTION THEREOF Unigen, Inc. (US) 2024-04-10 EP disclosed
CN-117794534-A Compositions for modulating cortisol homeostasis and improving sleep quality and methods of use and preparation thereof 尤尼根公司 2024-03-29 CN disclosed
WO-2022256624-A1 COMPOSITIONS FOR REGULATING HOMEOSTASIS OF CORTISOL AND IMPROVING SLEEP QUALITY AND METHODS OF USE AND PRODUCTION THEREOF UNIGEN, INC. (US) 2022-12-08 WO disclosed