Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 6/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HNF4A | P41235 | 1/20 | 0.39 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ASPH | Q12797 | 1/20 | 0.37 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3363273 | 0.82 | PTPN1 (0.45) | PTPN1TSHRHNF4AACMSDALDH1A1 | |
| SCHEMBL4249097 | 0.79 | ALDH1A1 (0.50) | PTPN1TSHRALDH1A1ALOX15KDM4E | |
| SCHEMBL27488099 | 0.79 | ALDH1A1 (0.54) | PTPN1TSHRHNF4AACMSDALDH1A1 | |
| SCHEMBL5455144 | 0.74 | ALDH1A1 (0.57) | PTPN1TSHRHNF4AACMSDALDH1A1 | |
| SCHEMBL6036619 | 0.74 | AKR1B1 (0.48) | TSHRALDH1A1KDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL26502 | 0.73 | HNF4A (0.53) | PTPN1TSHRHNF4AACMSDALDH1A1 | |
| SCHEMBL4777002 | 0.73 | TSHR (0.59) | PTPN1TSHRHNF4AACMSDALDH1A1 | |
| SCHEMBL4630736 | 0.73 | ALDH1A1 (0.55) | PTPN1TSHRHNF4AACMSDALDH1A1 | |
| SCHEMBL4191886 | 0.72 | ALDH1A1 (0.44) | HNF4AACMSDALDH1A1ALOX15KDM4E | |
| SCHEMBL9717027 | 0.71 | ALDH1A1 (0.53) | PTPN1TSHRHNF4AACMSDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100144872-A1 | New Methylenebisphenyl Compounds Useful in the Treatment of Inflammation | BIOLIPOX AB | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144872-A1 | New Methylenebisphenyl Compounds Useful in the Treatment of Inflammation | LTC4S, LTB4R2, LTB4R | PTPN1 2101/4885TSHR 1657/4885HNF4A 4415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.