⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4249133 | 0.84 | — | — | |
| SCHEMBL4067258 | 0.76 | PDF (0.38) | — | |
| SCHEMBL4067260 | 0.60 | BMP1 (0.39) | — | |
| SCHEMBL31158240 | 0.59 | FOLH1 (0.48) | — | |
| SCHEMBL11869594 | 0.59 | MMP1 (0.35) | — | |
| SCHEMBL31158244 | 0.59 | FOLH1 (0.48) | — | |
| SCHEMBL9854191 | 0.58 | CES2 (0.46) | — | |
| SCHEMBL3649585 | 0.58 | CA2 (0.58) | — | |
| SCHEMBL4059513 | 0.58 | BMP1 (0.47) | — | |
| SCHEMBL9562376 | 0.57 | CA2 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1585757-A4 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2009-04-22 | — | — | EP | claimed |
| JP-2006516120-A | — | — | 2006-06-22 | — | — | JP | claimed |
| EP-1585757-A2 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-10-19 | — | — | EP | claimed |
| WO-2004052919-A2 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-06-24 | — | — | WO | claimed |