Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 10/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTR1E | P28566 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4257247 | 0.89 | PKM (0.42) | ALDH1A1MAPTTP53 | |
| SCHEMBL4250409 | 0.84 | CRHBP (0.38) | ALDH1A1NPSR1HTTNPBWR1MAPT | |
| SCHEMBL4254527 | 0.80 | PRSS1 (0.34) | HTTNPBWR1MAPT | |
| SCHEMBL4252758 | 0.80 | MAOA (0.33) | CYP1A2CYP3A4CYP2C19NPBWR1MAPT | |
| SCHEMBL13608161 | 0.75 | ALDH1A1 (0.41) | ALDH1A1LMNANPSR1CYP1A2CYP3A4 | |
| SCHEMBL4254506 | 0.75 | ALDH1A1 (0.41) | ALDH1A1LMNANPSR1CYP1A2CYP3A4 | |
| SCHEMBL4257924 | 0.74 | HTT (0.41) | ALDH1A1LMNANPSR1CYP1A2CYP3A4 | |
| SCHEMBL4258922 | 0.72 | TSHR (0.36) | ALDH1A1TSHR | |
| SCHEMBL8214047 | 0.71 | ALDH1A1 (0.44) | ALDH1A1LMNANPSR1CYP1A2CYP3A4 | |
| SCHEMBL13619403 | 0.71 | PTGDR2 (0.38) | MAPTPOLBTP53HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090291959-A1 | CASPASE INHIBITORS BASED OF PYRIDAZINONE SCAFFOLD | LG LIFE SCIENCES LTD. (KR) | 2009-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090291959-A1 | CASPASE INHIBITORS BASED OF PYRIDAZINONE SCAFFOLD | CASP1, CASP2, CASP5 | ALDH1A1 3705/4885LMNA 114/4885NPSR1 4782/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.