SCHEMBL425509

SCHEMBL425509

C=CCN(CC=C)C(=O)c1ccccc1C(=O)N(CC=C)CC=C

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.52
ALDH1A1 P00352 7/20 0.49
HPGD P15428 3/20 0.49
POLB P06746 2/20 0.47
CYP3A4 P08684 1/20 0.46
CYP1A2 P05177 2/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
LMNA P02545 1/20 0.43
ALOX12 P18054 1/20 0.43
CCR6 P51684 1/20 0.43
TSHR P16473 3/20 0.42
KDM4E B2RXH2 4/20 0.41
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
HSD17B10 Q99714 1/20 0.40
MAPT P10636 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
HCRTR1 O43613 1/20 0.39
HCRTR2 O43614 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29370459 0.93 ALDH1A1 (0.50) TP53ALDH1A1HPGDPOLBCYP3A4
SCHEMBL21891711 0.93 ALDH1A1 (0.50) TP53ALDH1A1HPGDPOLBCYP3A4
SCHEMBL9764454 0.91 KDM4E (0.46) TP53ALDH1A1HPGDPOLBCYP3A4
SCHEMBL486061 0.89 TSHR (0.57) TP53ALDH1A1HPGDPOLBCYP3A4
SCHEMBL10653703 0.87 CES2 (0.47) TP53ALDH1A1HPGDPOLBCYP3A4
SCHEMBL10330497 0.87 TSHR (0.54) TP53ALDH1A1HPGDPOLBCYP3A4
SCHEMBL31517014 0.87 TSHR (0.54) TP53ALDH1A1HPGDPOLBCYP3A4
SCHEMBL8204818 0.84 ALDH1A1 (0.55) TP53ALDH1A1HPGDPOLBCYP3A4
SCHEMBL18205657 0.83 CTSD (0.49) TP53ALDH1A1HPGDPOLBLMNA
SCHEMBL10496233 0.83 KMT2A (0.49) TP53ALDH1A1HPGDSMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 184 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11279820-B2 Composition, method for producing heat-resistant vibration-proof material, and heat-resistant vibration-proof material KITAGAWA INDUSTRIES CO., LTD. (JP) 2022-03-22 US claimed
CN-111117481-B Addition type organic silicon liquid coating material and preparation method and application thereof 江苏微上新材料科技有限公司 2021-10-22 CN claimed
CN-111171716-A Epoxy silicone rubber coating material and preparation method and application thereof 江苏微上新材料科技有限公司 2020-05-19 CN claimed
CN-111117481-A Addition type organic silicon liquid coating material and preparation method and application thereof 江苏微上新材料科技有限公司 2020-05-08 CN claimed
EP-2805988-A1 METHOD FOR PRODUCING ACRYLIC RUBBER/FLUORO-RUBBER COMPOSITION, CROSSLINKED COMPOSITION, LAMINATE BODY, AND HEAT-RESISTANT AIR RUBBER HOSE Asahi Glass Company, Limited (JP) 2014-11-26 EP claimed
US-20140329096-A1 PROCESS FOR PRODUCING ACRYLIC RUBBER/FLUORINATED RUBBER COMPOSITION, CROSSLINKABLE COMPOSITION, LAMINATE AND HEAT RESISTANT AIR RUBBER HOSE ASAHI GLASS COMPANY, LIMITED (JP) 2014-11-06 US claimed
US-20260139136-A1 THERMOPLASTIC POLYMER COMPOSITION AND METHOD FOR PRODUCING THE SAME DAIKIN INDUSTRIES, LTD. (JP) 2026-05-21 US disclosed
EP-4696742-A1 RUBBER PRODUCT AND METHOD FOR PRODUCING SAME Mitsubishi Cable Industries, Ltd. (JP) 2026-02-18 EP disclosed
US-20250388728-A1 RUBBER COMPOSITION AND METHOD FOR PRODUCING RUBBER COMPOSITION AGC Inc. (JP) 2025-12-25 US disclosed
EP-4001322-B1 METHOD FOR PRODUCING FLUORINE-CONTAINING ELASTOMER, AND COMPOSITION DAIKIN IND LTD (JP) 2025-12-24 EP disclosed
EP-2804905-B1 FLUORORUBBER COMPOSITION DAIKIN IND LTD (JP) 2025-12-24 EP disclosed
US-20250368788-A1 RUBBER COMPOSITION, METHOD FOR PRODUCING RUBBER COMPOSITION, AND CROSSLINKED RUBBER ARTICLE AGC Inc. (JP) 2025-12-04 US disclosed
US-12473386-B2 Fluorine-containing elastomer, crosslinkable composition and molded article DAIKIN INDUSTRIES, LTD. (JP) 2025-11-18 US disclosed
US-20110086983-A1 THERMOPLASTIC POLYMER COMPOSITION AND PROCESS FOR PREPARING THERMOPLASTIC POLYMER COMPOSITION DAIKIN INDUSTRIES, LTD. (JP) 2011-04-14 US disclosed
US-20090226654-A1 Thermoplastic polymer composition and process for preparing thermoplastic polymer composition DAIKIN INDUSTRIES, LTD (JP) 2009-09-10 US disclosed
US-20090202769-A1 Thermoplastic Polymer Composition DAIKAN INDUSTRIES, LTD. (JP) 2009-08-13 US disclosed
US-20090011164-A1 Thermoplastic Polymer Composition DAIKIN INDUSTRIES, LTD (JP) 2009-01-08 US disclosed
EP-1826238-A1 THERMOPLASTIC POLYMER COMPOSITION AND PROCESS FOR PRODUCTION THEREOF Daikin Industries, Ltd. (JP) 2007-08-29 EP disclosed
EP-1816162-A1 THERMOPLASTIC POLYMER COMPOSITION Daikin Industries, Ltd. (JP) 2007-08-08 EP disclosed
EP-1816161-A1 THERMOPLASTIC POLYMER COMPOSITION Daikin Industries, Ltd. (JP) 2007-08-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260139136-A1 THERMOPLASTIC POLYMER COMPOSITION AND METHOD FOR PRODUCING THE SAME PFN1, RAD54L, FGB TP53 1936/4885ALDH1A1 4225/4885HPGD 2652/4885
US-20250388728-A1 RUBBER COMPOSITION AND METHOD FOR PRODUCING RUBBER COMPOSITION PFAS, RIF1, FRK TP53 1767/4885ALDH1A1 3676/4885HPGD 3836/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.