Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.71 |
| ▸ | CCR3 | P51677 | 1/20 | 0.69 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.66 |
| ▸ | HTR2A | P28223 | 3/20 | 0.64 |
| ▸ | HTR2C | P28335 | 2/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.64 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.58 |
| ▸ | DRD2 | P14416 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10522891 | 0.89 | SIGMAR1 (0.72) | CCR3HTR2AKCNH2SIGMAR1CYP1A2 | |
| SCHEMBL3149631 | 0.84 | CCR3 (0.73) | ACHECCR3SLC6A3HTR2AHTR2C | |
| SCHEMBL6056974 | 0.83 | SLC6A3 (0.83) | ACHECCR3SLC6A3KCNH2SIGMAR1 | |
| SCHEMBL14407778 | 0.83 | SLC6A3 (0.83) | ACHECCR3SLC6A3KCNH2SIGMAR1 | |
| SCHEMBL13150782 | 0.83 | SLC6A3 (0.83) | ACHECCR3SLC6A3KCNH2SIGMAR1 | |
| SCHEMBL7264546 | 0.83 | SLC6A3 (0.83) | ACHECCR3SLC6A3KCNH2SIGMAR1 | |
| SCHEMBL4252568 | 0.83 | ACHE (0.69) | ACHECCR3SLC6A3HTR2AHTR2C | |
| SCHEMBL152736 | 0.83 | ACHE (1.00) | ACHECCR3SLC6A3HTR2AHTR2C | |
| SCHEMBL4255190 | 0.83 | ACHE (0.69) | ACHECCR3SLC6A3HTR2AHTR2C | |
| SCHEMBL1803484 | 0.83 | ACHE (0.69) | ACHECCR3SLC6A3HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090239860-A1 | NOVEL BENZOFURAN DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND USES OF THESE | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-09-24 | — | — | US | disclosed |
| EP-1710233-A1 | NOVEL BENZOFURAN DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND USES OF THESE | Kissei Pharmaceutical Co., Ltd. (JP) | 2006-10-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090239860-A1 | NOVEL BENZOFURAN DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND USES OF THESE | ADORA2A, ADORA2B, HTR1F | ACHE 565/4885CCR3 2934/4885SLC6A3 498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.