Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4530562 | 0.77 | RAB9A (0.35) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL978551 | 0.77 | ALDH1A1 (0.57) | ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15 | |
| SCHEMBL7157961 | 0.77 | ALDH1A1 (0.57) | ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15 | |
| SCHEMBL4711303 | 0.76 | LTA4H (0.47) | TSHRMEN1KMT2APPARGTHRB | |
| SCHEMBL2097190 | 0.76 | ALDH1A1 (0.65) | ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15 | |
| SCHEMBL9861011 | 0.76 | ALDH1A1 (0.55) | ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15 | |
| SCHEMBL9860302 | 0.76 | ALDH1A1 (0.55) | ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15 | |
| SCHEMBL16340149 | 0.76 | ALDH1A1 (0.55) | ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15 | |
| SCHEMBL4260460 | 0.76 | THRB (0.39) | KMT2ATHRB | |
| SCHEMBL311913 | 0.76 | THRB (0.64) | ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0676062-A1 | PHOTODEFINABLE POLYMERS CONTAINING PERFLUOROCYCLOBUTANE GROUPS | THE DOW CHEMICAL COMPANY (US) | 1995-10-11 | — | — | EP | claimed |
| WO-1994015258-A1 | PHOTODEFINABLE POLYMERS CONTAINING PERFLUOROCYCLOBUTANE GROUPS | THE DOW CHEMICAL COMPANY (US) | 1994-07-07 | — | — | WO | claimed |
| US-8198375-B2 | Trifluorovinyl aromatic containing poly(alkyl ether) prepolymers | BAUSCH & LOMB INCORPORATED (US) | 2012-06-12 | — | — | US | disclosed |
| US-8183325-B2 | Mixture of polyoxyalkylene radical, polysiloxane radicals and perfluorocyclobutane radical; medical equipment; contact lenses | BAUSCH & LOMB INCORPORATED (US) | 2012-05-22 | — | — | US | disclosed |
| US-7582704-B2 | Biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 2009-09-01 | — | — | US | disclosed |
| US-20090192263-A1 | TRIFLUOROVINYL AROMATIC CONTAINING POLY(ALKYL ETHER) PREPOLYMERS | BAUSCH & LOMB MEXICO, S.A. DE C.V. (MX) | 2009-07-30 | — | — | US | disclosed |
| US-7544751-B2 | Polymerization products and biomedical devices containing same | BAUSCH & LOMB INCORPORATED (US) | 2009-06-09 | — | — | US | disclosed |
| US-7538160-B2 | Trifluorovinyl aromatic containing poly(alkyl ether) prepolymers | BAUSCH & LOMB INCORPORATED (US) | 2009-05-26 | — | — | US | disclosed |
| US-7534836-B2 | Polysiloxanes including cyclic polymers , polyethers, polyethersiloxanes with crosslinkable end groups including a dimerizable perfluorovinylphenyl group; polyperfluorocyclobutanes; contact/intraocular lenses; oxygen permeability; wettability' biocompatability; quality; prolonged eye contact | BAUSCH & LOMB INCORPORATED (US) | 2009-05-19 | — | — | US | disclosed |
| US-20080287626-A1 | Polymerization Products and Biomedical Devices Containing Same | PRZEDSIEBIORSTWO FARMACEUTYCZNE JELFA SPOLKA AKCYJNA (A/K/A PRZEDSIEBIORSTWO FARMACEUTYCZNE JELFA S.A.) (PL) | 2008-11-20 | — | — | US | disclosed |
| US-20080234454-A1 | PERFLUOROCYCLOBUTANE COPOLYMERS | PRZEDSIEBIORSTWO FARMACEUTYCZNE JELFA SPOLKA AKCYJNA (A/K/A PRZEDSIEBIORSTWO FARMACEUTYCZNE JELFA S.A.) (PL) | 2008-09-25 | — | — | US | disclosed |
| WO-2007005335-A1 | BIOMEDICAL DEVICES | BAUSCH & LOMB INCORPORATED (US) | 2007-01-11 | — | — | WO | disclosed |
| WO-2007005334-A1 | PERFLUOROCYCLOBUTANE COPOLYMERS | BAUSCH & LOMB INCORPORATED (US) | 2007-01-11 | — | — | WO | disclosed |
| WO-2007005355-A1 | TRIFLUOROVINYL AROMATIC CONTAINING POLY (ALKYL ETHER) PREPOLYMERS | BAUSCH & LOMB INCORPORATED (US) | 2007-01-11 | — | — | WO | disclosed |
| WO-2007005356-A1 | BIOMEDICAL DEVICES | BAUSCH & LOMB INCORPORATED (US) | 2007-01-11 | — | — | WO | disclosed |
| US-20070004897-A1 | Trifluorovinyl aromatic containing poly(alkyl ether) prepolymers | BAUSCH & LOMB INCORPORATED | 2007-01-04 | — | — | US | disclosed |
| US-20070004867-A1 | Perfluorocyclobutane copolymers | BAUSCH & LOMB INCORPORATED | 2007-01-04 | — | — | US | disclosed |
| US-20070004868-A1 | Polymerization products and biomedical devices containing same | BAUSCH & LOMB INCORPORATED | 2007-01-04 | — | — | US | disclosed |
| US-20070004866-A1 | Biomedical devices | BAUSCH & LOMB INCORPORATED | 2007-01-04 | — | — | US | disclosed |
| US-20070004886-A1 | Biomedical devices | BAUSCH & LOMB INCORPORATED | 2007-01-04 | — | — | US | disclosed |