Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.39 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12903696 | 0.81 | THRB (0.54) | THRBTHRAPLA2G1BKMT2AATG4B | |
| SCHEMBL4530562 | 0.78 | RAB9A (0.35) | ELANEKMT2A | |
| SCHEMBL4711303 | 0.78 | LTA4H (0.47) | THRBELANEKMT2A | |
| SCHEMBL9006509 | 0.76 | RAB9A (0.45) | THRBELANEKMT2A | |
| SCHEMBL8731268 | 0.76 | TRPA1 (0.36) | THRBELANEKMT2A | |
| SCHEMBL4256128 | 0.76 | ALDH1A1 (0.53) | THRBKMT2A | |
| SCHEMBL5538274 | 0.73 | LMNA (0.53) | THRBELANEKMT2A | |
| SCHEMBL13422210 | 0.73 | LTA4H (0.52) | CALM1ELANE | |
| SCHEMBL14369359 | 0.73 | S1PR1 (0.40) | THRBCALM1THRA | |
| SCHEMBL1505815 | 0.72 | KIF11 (0.39) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8198375-B2 | Trifluorovinyl aromatic containing poly(alkyl ether) prepolymers | BAUSCH & LOMB INCORPORATED (US) | 2012-06-12 | — | — | US | disclosed |
| US-8183325-B2 | Mixture of polyoxyalkylene radical, polysiloxane radicals and perfluorocyclobutane radical; medical equipment; contact lenses | BAUSCH & LOMB INCORPORATED (US) | 2012-05-22 | — | — | US | disclosed |
| US-7582704-B2 | Biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 2009-09-01 | — | — | US | disclosed |
| US-20090192263-A1 | TRIFLUOROVINYL AROMATIC CONTAINING POLY(ALKYL ETHER) PREPOLYMERS | BAUSCH & LOMB MEXICO, S.A. DE C.V. (MX) | 2009-07-30 | — | — | US | disclosed |
| US-7544751-B2 | Polymerization products and biomedical devices containing same | BAUSCH & LOMB INCORPORATED (US) | 2009-06-09 | — | — | US | disclosed |
| US-7538160-B2 | Trifluorovinyl aromatic containing poly(alkyl ether) prepolymers | BAUSCH & LOMB INCORPORATED (US) | 2009-05-26 | — | — | US | disclosed |
| US-7534836-B2 | Polysiloxanes including cyclic polymers , polyethers, polyethersiloxanes with crosslinkable end groups including a dimerizable perfluorovinylphenyl group; polyperfluorocyclobutanes; contact/intraocular lenses; oxygen permeability; wettability' biocompatability; quality; prolonged eye contact | BAUSCH & LOMB INCORPORATED (US) | 2009-05-19 | — | — | US | disclosed |
| US-20080287626-A1 | Polymerization Products and Biomedical Devices Containing Same | PRZEDSIEBIORSTWO FARMACEUTYCZNE JELFA SPOLKA AKCYJNA (A/K/A PRZEDSIEBIORSTWO FARMACEUTYCZNE JELFA S.A.) (PL) | 2008-11-20 | — | — | US | disclosed |
| US-20080234454-A1 | PERFLUOROCYCLOBUTANE COPOLYMERS | PRZEDSIEBIORSTWO FARMACEUTYCZNE JELFA SPOLKA AKCYJNA (A/K/A PRZEDSIEBIORSTWO FARMACEUTYCZNE JELFA S.A.) (PL) | 2008-09-25 | — | — | US | disclosed |
| US-7425600-B2 | Polymerization products and biomedical devices containing same | BAUSCH & LOMB INCORPORATED (US) | 2008-09-16 | — | — | US | disclosed |
| WO-2007005335-A1 | BIOMEDICAL DEVICES | BAUSCH & LOMB INCORPORATED (US) | 2007-01-11 | — | — | WO | disclosed |
| WO-2007005334-A1 | PERFLUOROCYCLOBUTANE COPOLYMERS | BAUSCH & LOMB INCORPORATED (US) | 2007-01-11 | — | — | WO | disclosed |
| WO-2007005355-A1 | TRIFLUOROVINYL AROMATIC CONTAINING POLY (ALKYL ETHER) PREPOLYMERS | BAUSCH & LOMB INCORPORATED (US) | 2007-01-11 | — | — | WO | disclosed |
| WO-2007005356-A1 | BIOMEDICAL DEVICES | BAUSCH & LOMB INCORPORATED (US) | 2007-01-11 | — | — | WO | disclosed |
| WO-2007005348-A1 | POLYMERIZATION PRODUCTS AND BIOMEDICAL DEVICES CONTAINING SAME | BAUSCH & LOMB INCORPORATED (US) | 2007-01-11 | — | — | WO | disclosed |
| US-20070004866-A1 | Biomedical devices | BAUSCH & LOMB INCORPORATED | 2007-01-04 | — | — | US | disclosed |
| US-20070004867-A1 | Perfluorocyclobutane copolymers | BAUSCH & LOMB INCORPORATED | 2007-01-04 | — | — | US | disclosed |
| US-20070004868-A1 | Polymerization products and biomedical devices containing same | BAUSCH & LOMB INCORPORATED | 2007-01-04 | — | — | US | disclosed |
| US-20070004886-A1 | Biomedical devices | BAUSCH & LOMB INCORPORATED | 2007-01-04 | — | — | US | disclosed |
| US-20070004897-A1 | Trifluorovinyl aromatic containing poly(alkyl ether) prepolymers | BAUSCH & LOMB INCORPORATED | 2007-01-04 | — | — | US | disclosed |