Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TAS2R8 | Q9NYW2 | 18/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4257939 | 0.79 | TSHR (0.40) | TSHRTAS2R8GRIN1GRIN2B | |
| SCHEMBL4259805 | 0.77 | TSHR (0.46) | TSHRTAS2R8 | |
| SCHEMBL4252950 | 0.77 | TAS2R8 (0.42) | TSHRTAS2R8 | |
| SCHEMBL4443541 | 0.73 | TSHR (0.45) | TSHRTAS2R8GRIN1GRIN2B | |
| SCHEMBL4258919 | 0.68 | TAS2R8 (0.37) | TSHRTAS2R8 | |
| SCHEMBL4252953 | 0.66 | TSHR (0.41) | TSHRTAS2R8 | |
| SCHEMBL4257924 | 0.61 | HTT (0.41) | — | |
| SCHEMBL4451137 | 0.61 | PKM (0.41) | — | |
| SCHEMBL4251545 | 0.61 | NPBWR1 (0.35) | TSHR | |
| SCHEMBL4256751 | 0.60 | ALDH1A1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090291959-A1 | CASPASE INHIBITORS BASED OF PYRIDAZINONE SCAFFOLD | LG LIFE SCIENCES LTD. (KR) | 2009-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090291959-A1 | CASPASE INHIBITORS BASED OF PYRIDAZINONE SCAFFOLD | CASP1, CASP2, CASP5 | TSHR 4747/4885TAS2R8 2870/4885GRIN1 4511/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.