SCHEMBL425896

SCHEMBL425896

CNCn1c(=O)[nH]cc(C(=O)O)c1=O

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC9A1 P19634 1/20 0.35
KDM4E B2RXH2 2/20 0.34
KDM3B Q7LBC6 1/20 0.34
ALDH1A1 P00352 2/20 0.33
KMT2A Q03164 1/20 0.33
FPR1 P21462 1/20 0.32
FPR2 P25090 1/20 0.32
CSNK2A1 P68400 3/20 0.32
CSNK2A2 P19784 2/20 0.32
CSNK2B P67870 2/20 0.32
CYP1A2 P05177 1/20 0.32
HSD17B10 Q99714 1/20 0.32
NOTUM Q6P988 1/20 0.32
PIM3 Q86V86 1/20 0.31
CLK4 Q9HAZ1 1/20 0.31
DYRK1A Q13627 1/20 0.31
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9054602 0.84 KDM3B (0.39) KDM4EKDM3BALDH1A1KMT2ACSNK2A1
SCHEMBL10823654 0.81 PDE4A (0.38) SLC9A1KDM4EKDM3BALDH1A1KMT2A
SCHEMBL459138 0.80 KDM4E (0.38) SLC9A1KDM4EKDM3BALDH1A1KMT2A
SCHEMBL10823648 0.77 B3GNT2 (0.46) SLC9A1KDM4EKDM3BALDH1A1KMT2A
SCHEMBL7586830 0.72 ALDH1A1 (0.42) KDM4EKDM3BALDH1A1KMT2ACSNK2A1
SCHEMBL19812558 0.70 KDM4E (0.41) KDM4EKDM3BALDH1A1KMT2ACSNK2A1
SCHEMBL14967362 0.68 DAO (0.42) KDM4EALDH1A1KMT2A
SCHEMBL16863256 0.68 KDM4E (0.41) KDM4EKDM3BALDH1A1KMT2ACSNK2A1
SCHEMBL425895 0.65 KMT2A (0.49) KDM4EKMT2ACYP1A2HSD17B10HPGD
SCHEMBL31091398 0.64 CYP2C9 (0.56) KDM4EALDH1A1KMT2ACYP1A2NOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 483 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260146073-A1 T CELL RECEPTORS TARGETING MUTATED CDKN2A THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVIC (US) 2026-05-28 US disclosed
US-12638452-B2 Nanopore assemblies and uses thereof OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2026-05-26 US disclosed
US-20250332186-A1 Methods and Compositions Relating to p62/SQSTM1 for the Treatment and Prevention of Inflammation-Associated Diseases CURELAB ONCOLOGY INC (US) 2025-10-30 US disclosed
US-20250263462-A1 ANTI-MUTATED KRAS T CELL RECEPTORS THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVIC (US) 2025-08-21 US disclosed
US-20250018040-A1 ANTI-MESOTHELIN POLYPEPTIDES, PROTEINS, AND CHIMERIC ANTIGEN RECEPTORS THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVIC (US) 2025-01-16 US disclosed
CN-118949941-A Nanopore assembly and uses thereof 牛津纳米孔科技公开有限公司 2024-11-15 CN disclosed
US-20240299510-A1 ANTIBODY-GUIDED PCSK9-MIMICKING IMMUNOGENS LACKING 9-RESIDUE SEQUENCE OVERLAP WITH HUMAN PROTEINS THE UNITED STATES OF AMERICA,AS REPRESENTED BY THE SECRETARY,DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2024-09-12 US disclosed
US-20240265999-A1 METHODS AND SYSTEMS FOR METAGENOMICS ANALYSIS IDBYDNA INC. 2024-08-08 US disclosed
US-12054742-B2 Compositions and methods to derive mesodermal lineage cells and mixed tissue organoids from embryonic stem cells REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2024-08-06 US disclosed
US-20240229051-A9 CHLOROPLAST CYTOSINE BASE EDITORS AND MITOCHONDRIA CYTOSINE BASE EDITORS IN PLANTS NATIONAL SCIENCE FOUNDATION 2024-07-11 US disclosed
WO-2001042305-A1 INTERLEUKIN-1 RECEPTOR ANTAGONIST-LIKE MOLECULES AND USES THEREOF AMGEN, INC. (US) 2001-06-14 WO disclosed
WO-2001042304-A1 INTERLEUKIN-1 RECEPTOR ANTAGONIST-RELATED MOLECULES AND USES THEREOF AMGEN, INC. (US) 2001-06-14 WO disclosed
WO-2001042465-A2 CHORDIN-LIKE MOLECULES AND USES THEREOF AMGEN, INC. (US) 2001-06-14 WO disclosed
WO-2001011050-A1 Fhm, A NOVEL MEMBER OF THE TNF LIGAND SUPERGENE FAMILY AMGEN INC. (US) 2001-02-15 WO disclosed
WO-2001010908-A1 NTR3, A MEMBER OF THE TNF-RECEPTOR SUPERGENE FAMILY AMGEN INC. (US) 2001-02-15 WO disclosed
WO-2001007074-A1 VGF SELECTIVE BINDING AGENTS AND METHODS OF TREATING VGF-RELATED DISORDERS AMGEN, INC. (US) 2001-02-01 WO disclosed
WO-2001007477-A1 VGF POLYPEPTIDES AND METHODS OF TREATING VGF-RELATED DISORDERS AMGEN, INC. (US) 2001-02-01 WO disclosed
EP-0476071-A4 EXONUCLEASE-RESISTANT OLIGONUCLEOTIDES AND METHODS FOR PREPARING THE SAME 1992-11-04 EP disclosed
EP-0476071-A1 EXONUCLEASE-RESISTANT OLIGONUCLEOTIDES AND METHODS FOR PREPARING THE SAME GILEAD SCIENCES, INC. (US) 1992-03-25 EP disclosed
WO-1990015065-A1 EXONUCLEASE-RESISTANT OLIGONUCLEOTIDES AND METHODS FOR PREPARING THE SAME GILEAD SCIENCES, INC. (US) 1990-12-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260146073-A1 T CELL RECEPTORS TARGETING MUTATED CDKN2A TP53, CD74, HLA-C SLC9A1 4194/4885KDM4E 1921/4885KDM3B 804/4885
US-12638452-B2 Nanopore assemblies and uses thereof FAM83A, SCNN1G, SCN3A SLC9A1 422/4885KDM4E 4393/4885KDM3B 3989/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.