Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM3B | Q7LBC6 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CCR6 | P51684 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.31 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL425896 | 0.84 | SLC9A1 (0.35) | KDM3BCSNK2A1PIM3CLK4KDM4E | |
| SCHEMBL7547639 | 0.74 | KDM3B (0.46) | KDM3BCSNK2A1PIM3CLK4KDM4E | |
| SCHEMBL10823654 | 0.69 | PDE4A (0.38) | KDM3BCSNK2A1PIM3CLK4KDM4E | |
| SCHEMBL459138 | 0.67 | KDM4E (0.38) | KDM3BCSNK2A1PIM3CLK4KDM4E | |
| SCHEMBL9054601 | 0.67 | KDM3B (0.39) | KDM3BKDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL4278697 | 0.66 | MPO (0.34) | KDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL10823648 | 0.66 | B3GNT2 (0.46) | KDM3BKDM4EALDH1A1KMT2ATDP1 | |
| SCHEMBL7586830 | 0.63 | ALDH1A1 (0.42) | KDM3BCSNK2A1PIM3CLK4KDM4E | |
| SCHEMBL19812558 | 0.60 | KDM4E (0.41) | KDM3BCSNK2A1PIM3CLK4KDM4E | |
| SCHEMBL15798472 | 0.60 | NR4A2 (0.41) | KDM4EALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996008559-A1 | GLYCOSAMINOGLYCAN-DEGRADING ENZYME INHIBITION AND RESULTANT DISEASE THERAPIES | CARDIAC CRC NOMINEES PTY. LTD. (AU) | 1996-03-21 | — | — | WO | disclosed |