SCHEMBL4259054

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1086587	0.89	MEN1 (0.43)	MEN1KMT2ANPC1RIPK1CYP3A4
	SCHEMBL1086810	0.85	MEN1 (0.46)	MEN1KMT2ARIPK1HPGD
	SCHEMBL1086489	0.84	ALDH1A1 (0.46)	MEN1KMT2ANPC1RIPK1CYP2D6
	SCHEMBL1086649	0.83	CYP3A4 (0.42)	RIPK1CYP3A4CYP2D6CYP2C19CYP2C9
	SCHEMBL1086756	0.83	CCR3 (0.42)	NPC1RIPK1GRM2MMP13HDAC1
	SCHEMBL1086246	0.83	RIPK1 (0.49)	MEN1KMT2ANPC1RIPK1POLB
	SCHEMBL1086470	0.82	FAAH (0.42)	MEN1KMT2ACYP3A4CYP2D6GRM2
	SCHEMBL4486191	0.81	MMP13 (0.40)	KMT2AGRM2MMP13HDAC1TACR2
	SCHEMBL1086449	0.80	MGLL (0.44)	MEN1KMT2ARIPK1
	SCHEMBL1086445	0.80	P2RX7 (0.40)	TACR2TACR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.