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SCHEMBL426348

SCHEMBL426348

O=C(O)CC(O)(CC(=O)OCC(COC(=O)CC(O)(CC(=O)O)C(=O)O)OC(=O)CC(O)(CC(=O)O)C(=O)O)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.52
▸ LMNA P02545 2/20 0.37
▸ KDM4E B2RXH2 2/20 0.33
▸ PRKCA P17252 2/20 0.33
▸ CPT2 P23786 1/20 0.32
▸ ACLY P53396 1/20 0.32
▸ MAPT P10636 2/20 0.31
▸ ALOX15 P16050 1/20 0.31
▸ TSHR P16473 1/20 0.31
▸ PRKCE Q02156 1/20 0.31
▸ PRKCQ Q04759 1/20 0.31
▸ PRKCD Q05655 1/20 0.31
▸ LPAR3 Q9UBY5 3/20 0.31
▸ LPAR1 Q92633 2/20 0.31
▸ ENPP2 Q13822 1/20 0.31
▸ SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL431227 0.92 ALDH1A1 (0.47) ALDH1A1PRKCAPRKCEPRKCQPRKCD
SCHEMBL423239 0.91 ALDH1A1 (0.46) ALDH1A1LMNAKDM4EPRKCAMAPT
SCHEMBL429385 0.88 ALDH1A1 (0.43) ALDH1A1LMNAKDM4EPRKCAMAPT
Ethylene Glycol SCHEMBL423238 0.87 ALDH1A1 (0.42) ALDH1A1LMNAKDM4EPRKCAMAPT
SCHEMBL431247 0.85 ALDH1A1 (0.41) ALDH1A1LMNAPRKCAACLYPRKCE
SCHEMBL425248 0.85 ALDH1A1 (0.41) ALDH1A1LMNAKDM4E
SCHEMBL424041 0.85 ALDH1A1 (0.42) ALDH1A1LMNAPRKCATSHRPRKCE
SCHEMBL537042 0.84 ALDH1A1 (0.40) ALDH1A1LMNAKDM4EMAPTALOX15
SCHEMBL427083 0.84 ALDH1A1 (0.44) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL428393 0.83 ALDH1A1 (0.48) ALDH1A1LMNAKDM4ECPT2ACLY

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120020906-A1 ANTIPERSPIRANT SPRAYS WITH ESTER OILS HENKEL AG & CO. KGAA (DE) 2012-01-26 — — US claimed
CN-118829433-A Respiratory stimulant parenteral formulations 依那拉治疗股份有限公司 2024-10-22 — — CN disclosed
CN-118488840-A Methods of treating respiratory depression modulated by non-opioid agents 依那拉治疗股份有限公司 2024-08-13 — — CN disclosed
CN-117529306-A Nicotinamide Adenine Dinucleotide (NAD) compositions, methods of making and methods of using the same 索维达解决方案有限公司 2024-02-06 — — CN disclosed
CN-117479945-A Large conductance potassium channel modulators, compositions thereof, methods of making and methods of using the same 依那拉治疗股份有限公司 2024-01-30 — — CN disclosed
EP-3192499-B1 CELLULOSE FIBRE BASED SUPPORT MATRICES FOR LAYERED PRODUCTS FOR ORAL AND PERORAL APPLICATION AND THEIR PREPARATION GLATT GMBH (DE) 2023-11-29 — — EP disclosed
CN-111511434-B Oral delivery of active drug substances 柏欧格瑞有限责任公司 2023-03-17 — — CN disclosed
CN-111491603-A Composition for removing nail polish 莱雅公司 2020-08-04 — — CN disclosed
US-20170157025-A1 TEXTILE FRIENDLY ANTIPERSPIRANT COMPOSITIONS HENKEL AG & CO. KGAA (DE) 2017-06-08 — — US disclosed
US-9402762-B2 Methods and devices for conduit occlusion FEMASYS INC. 2016-08-02 — — US disclosed
US-20150068531-A1 METHODS AND DEVICES FOR CONDUIT OCCLUSION FEMASYS INC. (US) 2015-03-12 — — US disclosed
US-8828367-B2 Water-free antiperspirant non-aerosols in which active substances are more readily released HENKEL AG & CO. KGAA (DE) 2014-09-09 — — US disclosed
US-8603445-B2 Water-free antiperspirant sprays in which active substances are more readily released HENKEL AG & CO. KGAA (DE) 2013-12-10 — — US disclosed
US-20120177589-A1 WATER-FREE ANTIPERSPIRANT NON-AEROSOLS IN WHICH ACTIVE SUBSTANCES ARE MORE READILY RELEASED HENKEL AG & CO. KGAA (DE) 2012-07-12 — — US disclosed
US-20120171143-A1 WATER-FREE ANTIPERSPIRANT SPRAYS IN WHICH ACTIVE SUBSTANCES ARE MORE READILY RELEASED HENKEL AG & CO. KGAA (DE) 2012-07-05 — — US disclosed
US-20120020906-A1 ANTIPERSPIRANT SPRAYS WITH ESTER OILS HENKEL AG & CO. KGAA (DE) 2012-01-26 — — US disclosed
US-5508394-A BUILDERS IN LOW(OR NO)PHOSPHATE DETERGENTS BASF AKTIENGESELLSCHAFT (DE) 1996-04-16 — — US disclosed
US-3859224-A DETERGENT COMPOSITION CONTAINING, AS A BUILDER, THE SODIUM SALT OF GLYCEROL TRICITRATE HOECHST AG 1975-01-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120020906-A1 ANTIPERSPIRANT SPRAYS WITH ESTER OILS CUTA, NAPEPLD, LIPE ALDH1A1 1032/4885LMNA 3398/4885KDM4E 2642/4885
US-20120177589-A1 WATER-FREE ANTIPERSPIRANT NON-AEROSOLS IN WHICH ACTIVE SUBSTANCES ARE MORE READILY RELEASED SIGMAR1, POLR1C, CUTA ALDH1A1 2601/4885LMNA 3148/4885KDM4E 3572/4885
US-20120171143-A1 WATER-FREE ANTIPERSPIRANT SPRAYS IN WHICH ACTIVE SUBSTANCES ARE MORE READILY RELEASED POLR1C, CUTA, PHOSPHO1 ALDH1A1 1827/4885LMNA 2595/4885KDM4E 3267/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.