Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 5/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4265822 | 0.87 | DNM1 (0.37) | DNM1PLA2G1BPLA2G2AOPRM1TSHR | |
| SCHEMBL4265723 | 0.87 | PLA2G1B (0.32) | DNM1PLA2G1BPLA2G2AFDPSTSHR | |
| SCHEMBL4268208 | 0.82 | FDPS (0.33) | PLA2G1BPLA2G2AFDPS | |
| SCHEMBL4263660 | 0.80 | MMP1 (0.30) | — | |
| SCHEMBL487874 | 0.75 | LMNA (0.54) | DNM1FDPSLMNAOPRM1TSHR | |
| Hydrochloric Acid SCHEMBL9284196 | 0.75 | HTT (0.42) | DNM1PLA2G1BPLA2G2ATHRB | |
| Hydrochloric Acid SCHEMBL9289575 | 0.75 | HTT (0.42) | DNM1PLA2G1BPLA2G2ATHRB | |
| Hydrochloric Acid SCHEMBL9287174 | 0.75 | HTT (0.42) | DNM1PLA2G1BPLA2G2ATHRB | |
| Hydrochloric Acid SCHEMBL9289589 | 0.75 | HTT (0.42) | DNM1PLA2G1BPLA2G2ATHRB | |
| SCHEMBL28639819 | 0.74 | DNM1 (0.42) | DNM1PLA2G1BPLA2G2AFDPSLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399570-B2 | Functionalized polymers and improved tires therefrom | BRIDGESTONE CORPORATION (JP) | 2013-03-19 | — | — | US | disclosed |
| US-20090326161-A1 | FUNCTIONALIZED POLYMERS AND IMPROVED TIRES THEREFROM | BRIDGESTONE CORPORATION (JP) | 2009-12-31 | — | — | US | disclosed |
| US-7598322-B1 | particularly tire treads exhibiting reduced rolling resistance; a vulcanized rubbery polymer such as polybutadiene-butadiene-styrene copolymer made from living polymerization using butyllithium initiator and a tributyloxyborane as polymerization terminator | BRIDGESTONE CORPORATION (JP) | 2009-10-06 | — | — | US | disclosed |