SCHEMBL4264574

SCHEMBL4264574

CC(C)C[C@H](NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](N)C(C)C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ LNPEP Q9UIQ6 5/20 0.58
▸ REN P00797 12/20 0.54
▸ ANPEP P15144 1/20 0.51
▸ CTSD P07339 1/20 0.50
▸ TRHR P34981 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29636378 0.90 LNPEP (0.54) LNPEPRENANPEPCTSD
SCHEMBL19345095 0.82 TRHR (0.61) LNPEPRENCTSDTRHR
SCHEMBL30661445 0.82 ACE (0.47) REN
SCHEMBL30661449 0.82 ACE (0.47) REN
SCHEMBL30051606 0.82 ACE (0.49) REN
SCHEMBL30253567 0.81 LNPEP (0.76) LNPEPRENANPEP
SCHEMBL31435690 0.80 REN (0.58) RENCTSDTRHR
SCHEMBL4959538 0.79 TRHR (0.64) LNPEPRENCTSDTRHR
SCHEMBL30498898 0.79 CAPN1 (0.49) REN
SCHEMBL21838312 0.79 SLC15A2 (0.54) LNPEPRENANPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090036363-A1 Peptides as cell penetrating carriers UNIVERSIDAD DE BARCELONA (ES) 2009-02-05 — — US disclosed
EP-1724280-A1 USE OF PEPTIDES AS PENETRATING CELL CARRIERS UNIVERSIDAD DE BARCELONA (ES) 2006-11-22 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090036363-A1 Peptides as cell penetrating carriers ARGLU1, SLC7A1, ARG1 LNPEP 7/4885REN 2209/4885ANPEP 16/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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