Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | PRKCA | P17252 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ESRRA | P11474 | 1/20 | 0.38 |
| ▸ | MAT2A | P31153 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3593431 | 0.99 | ATM (0.51) | ATMSMN1; SMN2ALOX5PRKCAGSK3B | |
| SCHEMBL4264276 | 0.87 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1KMT2AALOX15POLB | |
| Hydrochloric Acid SCHEMBL3607615 | 0.86 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1KMT2AALOX15POLB | |
| Hydrochloric Acid SCHEMBL3603516 | 0.84 | LMNA (0.44) | ATMALOX5LMNAALDH1A1KMT2A | |
| SCHEMBL3601347 | 0.82 | ALOX5 (0.43) | ALOX5 | |
| Hydrochloric Acid SCHEMBL3602867 | 0.81 | ALOX5 (0.42) | ALOX5 | |
| SCHEMBL3597579 | 0.80 | ADRB1 (0.48) | ALOX5ALDH1A1KMT2A | |
| Bromide SCHEMBL3602839 | 0.78 | MAPT (0.42) | ATMSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL4266773 | 0.78 | ALOX5 (0.49) | ATMSMN1; SMN2ALOX5PRKCAGSK3B | |
| Hydrochloric Acid SCHEMBL3604157 | 0.77 | ADRB1 (0.49) | SMN1; SMN2ALOX5ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2039695-A1 | BICYCLIC HETEROCYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2009-03-25 | — | — | EP | disclosed |