Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.54 |
| ▸ | TYMS | P04818 | 3/20 | 0.53 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.52 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.50 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.50 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.47 |
| ▸ | CETP | P11597 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4277260 | 0.79 | ACHE (0.55) | KDRCHRNB4CHRNA3CHRNA7MMP2 | |
| SCHEMBL4271367 | 0.79 | KDR (0.54) | KDRMMP2MMP9MMP8MMP13 | |
| SCHEMBL9232601 | 0.75 | TYMS (0.62) | KDRTYMSLMNAKMT2A | |
| SCHEMBL4272926 | 0.74 | CA2 (0.60) | KDRLMNAKMT2AEGFRERBB2 | |
| SCHEMBL30988953 | 0.73 | GLA (0.61) | KDRLMNAKMT2AEGFRERBB2 | |
| SCHEMBL8983546 | 0.72 | RAB9A (0.61) | TLR9CHRNB4CHRNA3CHRNA7CHRNA10 | |
| SCHEMBL22089506 | 0.72 | PTK2 (0.54) | KDRLMNAKMT2AEGFRERBB2 | |
| SCHEMBL11137597 | 0.71 | CHRNB4 (0.67) | TLR9CHRNB4CHRNA3CHRNA7CHRNA10 | |
| SCHEMBL29256777 | 0.71 | GLA (0.59) | KDRLMNAKMT2AEGFRERBB2 | |
| SCHEMBL9612685 | 0.71 | ALDH1A1 (0.52) | KDRLMNAKMT2AEGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2085394-B1 | Metronidazole derivatives as antiparasitic agents | UNIV JORDAN (JO) | 2012-06-06 | — | — | EP | disclosed |
| EP-2085394-A2 | Metronidazole derivatives as antiparasitic agents | Legal Affairs Office University of Jordan (JO) | 2009-08-05 | — | — | EP | disclosed |