Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.54 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | ATP4A | P20648 | 4/20 | 0.49 |
| ▸ | ATP4B | P51164 | 4/20 | 0.49 |
| ▸ | EGFR | P00533 | 2/20 | 0.48 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4277260 | 0.79 | ACHE (0.55) | KDRMMP2MMP9MMP8ATP4A | |
| SCHEMBL4267151 | 0.79 | KDR (0.54) | KDRMMP2MMP9MMP8MMP13 | |
| SCHEMBL9229976 | 0.76 | TYMS (0.52) | KDRSMN1; SMN2MEN1ALDH1A1HPGD | |
| SCHEMBL30988953 | 0.75 | GLA (0.61) | KDREGFRERBB2ALDH1A1TSHR | |
| SCHEMBL4272926 | 0.74 | CA2 (0.60) | KDREGFRERBB2ALDH1A1TSHR | |
| SCHEMBL15462904 | 0.73 | ATP4A (0.83) | APPMMP9MMP8ATP4AATP4B | |
| SCHEMBL22089506 | 0.72 | PTK2 (0.54) | KDREGFRERBB2ALDH1A1TSHR | |
| SCHEMBL22104306 | 0.70 | LMNA (0.53) | KDREGFRERBB2ALDH1A1TSHR | |
| SCHEMBL13198328 | 0.70 | KDM4E (0.70) | APPMMP9MMP8ATP4AATP4B | |
| SCHEMBL19229535 | 0.70 | ATP4A (0.78) | APPMMP9MMP8ATP4AATP4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2085394-B1 | Metronidazole derivatives as antiparasitic agents | UNIV JORDAN (JO) | 2012-06-06 | — | — | EP | disclosed |
| EP-2085394-A2 | Metronidazole derivatives as antiparasitic agents | Legal Affairs Office University of Jordan (JO) | 2009-08-05 | — | — | EP | disclosed |