Sugi Predict

Sugi Predict / Compounds / SCHEMBL427058

SCHEMBL427058

SCHEMBL427058

O=C(Cl)n1nnc2ccccc21

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 11/20 0.64
▸ MGAM O43451 10/20 0.64
▸ AMY1A P0DUB6 10/20 0.64
▸ SI P14410 10/20 0.64
▸ MGAM2 Q2M2H8 10/20 0.64
▸ KMT2A Q03164 3/20 0.64
▸ F2 P00734 2/20 0.64
▸ HPGD P15428 1/20 0.64
▸ SLC9A1 P19634 1/20 0.64
▸ DGAT1 O75907 1/20 0.61
▸ F12 P00748 6/20 0.61
▸ KCNMA1 Q12791 1/20 0.58
▸ GLA P06280 1/20 0.55
▸ THRB P10828 1/20 0.55
▸ KDM4E B2RXH2 1/20 0.54
▸ ALDH1A1 P00352 1/20 0.54
▸ MAPT P10636 1/20 0.54
▸ HTT P42858 1/20 0.54
▸ NPSR1 Q6W5P4 1/20 0.54
▸ MIF P14174 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL706083 0.84 MGAM (0.68) GAAMGAMAMY1ASIMGAM2
SCHEMBL4250719 0.84 GAA (0.68) GAAMGAMAMY1ASIMGAM2
SCHEMBL170673 0.82 GAA (0.71) GAAMGAMAMY1ASIMGAM2
SCHEMBL1756653 0.82 DGAT1 (0.69) GAAMGAMAMY1ASIMGAM2
SCHEMBL14325836 0.81 DGAT1 (0.58) GAAMGAMAMY1ASIMGAM2
Ammonia Solution, Strong SCHEMBL3505685 0.81 GAA (0.69) GAAMGAMAMY1ASIMGAM2
SCHEMBL443991 0.81 GAA (0.64) GAAMGAMAMY1ASIMGAM2
Hydrochloric Acid SCHEMBL10363645 0.81 GAA (0.69) GAAMGAMAMY1ASIMGAM2
SCHEMBL3840404 0.81 GAA (0.69) GAAMGAMAMY1ASIMGAM2
SCHEMBL10621117 0.81 GAA (0.64) GAAMGAMAMY1ASIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 192 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2014797-A2 Coating composition for interconnection part of electrode and plasma display panel including the same Samsung SDI Co., Ltd. (KR) 2009-01-14 — — EP claimed
US-20080303439-A1 Coating composition for interconnection part of electrode and plasma display panel including the same SAMSUNG SDI CO., LTD., A CORP. OF THE REPUBLIC OF KOREA (KR) 2008-12-11 — — US claimed
CN-100366616-C Novel bicyclic inhibitors of hormone sensitive lipase AVENTIS PHARMA GMBH (DE) 2008-02-06 — — CN claimed
US-7208504-B2 Bicyclic inhibitors of hormone sensitive lipase SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2007-04-24 — — US claimed
CN-1688555-A Novel bicyclic inhibitors of hormone sensitive lipase AVENTIS PHARMA GMBH (DE) 2005-10-26 — — CN claimed
US-20040127484-A1 Novel bicyclic inhibitors of hormone sensitive lipase AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2004-07-01 — — US claimed
CN-121271120-A Corrosion-resistant PVC printing film and preparation method thereof 南通吉美装饰材料有限公司 2026-01-06 — — CN disclosed
WO-2023152711-A1 PROCESS FOR THE PREPARATION OF CENOBAMATE AND INTERMEDIATES THEREOF METROCHEM API PVT LTD (IN) 2023-08-17 — — WO disclosed
US-20190345190-A1 PHOSPHONATE ANALOGS OF HIV INHIBITOR COMPOUNDS GILEAD SCIENCES, INC. 2019-11-14 — — US disclosed
US-20190315785-A1 PHOSPHONATE ANALOGS OF HIV INHIBITOR COMPOUNDS GILEAD SCIENCES, INC. 2019-10-17 — — US disclosed
US-20180086784-A1 Phosphonate analogs of HIV inhibitor compounds GILEAD SCIENCES, INC. 2018-03-29 — — US disclosed
US-20180086784-A1 Phosphonate analogs of HIV inhibitor compounds GILEAD SCIENCES, INC. 2018-03-29 — — US disclosed
US-20170210770-A1 PHOSPHONATE ANALOGS OF HIV INHIBITOR COMPOUNDS GILEAD SCIENCES, INC. 2017-07-27 — — US disclosed
EP-0520498-A1 Method of preparation of photographic coupler EASTMAN KODAK COMPANY (US) 1992-12-30 — — EP disclosed
EP-0147211-B1 4H-3,1-BENZOXAZIN-4-ONES AND RELATED COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESSES FOR THEIR PREPARATION SYNTEX (U.S.A.) INC. (US) 1990-09-12 — — EP disclosed
US-4942248-A CARBAMYLATION OF AMINO ACIDS BY REACTION WITH TERT-ALKYL ESTER A OF 1H-BENZOTRIAZOLE-1-CARBOXYLIC ACID TO FOR BLOCKED AMINO GROUP PPG INDUSTRIES, INC. (US) 1990-07-17 — — US disclosed
US-4793948-A ANTICARCINOGENIC AGENTS WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) 1988-12-27 — — US disclosed
EP-0232788-A1 Bile acid derivatives and production thereof WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) 1987-08-19 — — EP disclosed
US-4657893-A ANTIINFLAMMATORY AGENTS SYNTEX (U.S.A.) INC. (US) 1987-04-14 — — US disclosed
EP-0147211-A2 4H-3,1-benzoxazin-4-ones and related compounds, pharmaceutical compositions containing them, and processes for their preparation SYNTEX (U.S.A.) INC. (US) 1985-07-03 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190315785-A1 PHOSPHONATE ANALOGS OF HIV INHIBITOR COMPOUNDS PIK3CA, TYMP, ITPA GAA 385/4885MGAM 1545/4885AMY1A 4853/4885
US-20190345190-A1 PHOSPHONATE ANALOGS OF HIV INHIBITOR COMPOUNDS PIK3CA, TYMP, ITPA GAA 385/4885MGAM 1545/4885AMY1A 4853/4885
US-20180086784-A1 Phosphonate analogs of HIV inhibitor compounds PIK3CA, TYMP, ITPA GAA 385/4885MGAM 1545/4885AMY1A 4853/4885
US-20170210770-A1 PHOSPHONATE ANALOGS OF HIV INHIBITOR COMPOUNDS PIK3CA, TYMP, ITPA GAA 385/4885MGAM 1545/4885AMY1A 4853/4885
US-20040127484-A1 Novel bicyclic inhibitors of hormone sensitive lipase LIPE, PNLIP, CEL GAA 283/4885MGAM 691/4885AMY1A 26/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.