Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13804029 | 0.86 | LMNA (0.36) | SIGMAR1 | |
| SCHEMBL2691080 | 0.85 | SIGMAR1 (0.37) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL1399926 | 0.84 | LMNA (0.38) | — | |
| SCHEMBL8971010 | 0.78 | MAOA (0.50) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL9568957 | 0.76 | SIGMAR1 (0.34) | SIGMAR1 | |
| SCHEMBL3841650 | 0.76 | QDPR (0.43) | — | |
| SCHEMBL4233609 | 0.75 | SIGMAR1 (0.60) | ALDH1A1MAPTSMN1; SMN2SIGMAR1 | |
| Hydrochloric Acid SCHEMBL11074886 | 0.74 | QDPR (0.42) | — | |
| Hydrochloric Acid SCHEMBL9704069 | 0.74 | QDPR (0.42) | — | |
| SCHEMBL13564385 | 0.72 | HTR6 (0.42) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2116543-A1 | NOVEL AMINOPYRIMIDINE DERIVATIVE AS PLK1 INHIBITOR | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2009-11-11 | — | — | EP | disclosed |