Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL68310 | 0.91 | KDM4E (0.56) | KDM4EL3MBTL1TDP1EGFRATM | |
| SCHEMBL12508634 | 0.86 | KDM4E (0.52) | KDM4EL3MBTL1TDP1EGFRATM | |
| SCHEMBL13972696 | 0.85 | KDM4E (0.49) | KDM4EL3MBTL1TDP1EGFRATM | |
| SCHEMBL13576829 | 0.83 | KDM4E (0.53) | KDM4EL3MBTL1TDP1EGFRATM | |
| SCHEMBL13441760 | 0.83 | PKM (0.56) | KDM4EL3MBTL1EGFRCA12CA1 | |
| SCHEMBL25285645 | 0.82 | IAPP (0.51) | KDM4EEGFRCA12CA1CA2 | |
| SCHEMBL30311288 | 0.82 | AKR1B1 (0.61) | KDM4EEGFRATMCA12CA1 | |
| SCHEMBL392976 | 0.82 | AKR1B1 (0.61) | KDM4EEGFRATMCA12CA1 | |
| SCHEMBL29503119 | 0.81 | L3MBTL1 (0.68) | KDM4EL3MBTL1TDP1ATMHPGD | |
| SCHEMBL2981629 | 0.81 | ALDH1A1 (0.50) | KDM4EEGFRATMCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090069373-A1 | Quinoline Acids | WYETH (US) | 2009-03-12 | — | — | US | disclosed |
| US-20090004485-A1 | 6-MEMBER RING STRUCTURE USED IN ELECTROLUMINESCENT DEVICES | GLOBAL OLED TECHNOLOGY LLC | 2009-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090004485-A1 | 6-MEMBER RING STRUCTURE USED IN ELECTROLUMINESCENT DEVICES | SOD1, SCO2, SOD3 | KDM4E 1903/4885L3MBTL1 3673/4885TDP1 4286/4885 |
| US-20090069373-A1 | Quinoline Acids | NR1H3, NR1H2, NR1H4 | KDM4E 2746/4885L3MBTL1 2944/4885TDP1 4345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.