SCHEMBL4273571

SCHEMBL4273571

CC(=O)N(C(C)=O)[C@@H](CCCNC(=N)N)C(=O)O

nearest known ligand 0.34

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
CYP1A2 P05177 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
GAA P10253 1/20 0.33
NOS3 P29474 1/20 0.33
NOS1 P29475 1/20 0.33
NOS2 P35228 1/20 0.33
OTC P00480 1/20 0.32
NPY4R P50391 8/20 0.32
NPY1R P25929 5/20 0.32
NPY2R P49146 3/20 0.32
NPY5R Q15761 3/20 0.32
ALB P02768 1/20 0.31
DDAH1 O94760 1/20 0.31
ITGB3 P05106 2/20 0.31
ITGA2B P08514 2/20 0.31
FOLH1 Q04609 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4273557 1.00 ALOX15 (0.34) ALOX15MEN1KMT2ACYP1A2SMN1; SMN2
SCHEMBL2673036 0.87 ALOX15 (0.36) ALOX15MEN1KMT2ACYP1A2SMN1; SMN2
SCHEMBL2673040 0.87 ALOX15 (0.36) ALOX15MEN1KMT2ACYP1A2SMN1; SMN2
SCHEMBL30581622 0.86 FOLH1 (0.36) ALOX15MEN1KMT2ACYP1A2SMN1; SMN2
SCHEMBL28406813 0.86 FOLH1 (0.36) ALOX15MEN1KMT2ACYP1A2SMN1; SMN2
SCHEMBL4191476 0.85 OTC (0.33) ALOX15MEN1KMT2ACYP1A2SMN1; SMN2
SCHEMBL4191486 0.85 OTC (0.33) ALOX15MEN1KMT2ACYP1A2SMN1; SMN2
SCHEMBL160690 0.84 NOS2 (0.38) ALOX15MEN1KMT2ACYP1A2SMN1; SMN2
SCHEMBL196827 0.84 NOS2 (0.38) ALOX15MEN1KMT2ACYP1A2SMN1; SMN2
SCHEMBL288819 0.84 NOS2 (0.38) ALOX15MEN1KMT2ACYP1A2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117355321-A Performance enhancing excipients and methods for reducing viscosity and improving stability of biological agents 安万托特性材料股份有限公司 2024-01-05 CN claimed
CN-117355321-A Performance enhancing excipients and methods for reducing viscosity and improving stability of biological agents 安万托特性材料股份有限公司 2024-01-05 CN disclosed
CN-117355321-A Performance enhancing excipients and methods for reducing viscosity and improving stability of biological agents 安万托特性材料股份有限公司 2024-01-05 CN disclosed
US-7608250-B2 Cosmetic composition AJINOMOTO CO., INC. (JP) 2009-10-27 US disclosed
US-20060029626-A1 Cosmetic composition AJINOMOTO CO., INC. (JP) 2006-02-09 US disclosed
US-20030165448-A1 Cosmetic composition AJINOMOTO CO., INC. (JP) 2003-09-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030165448-A1 Cosmetic composition CUTA, ARGLU1, ASS1 ALOX15 1079/4885MEN1 291/4885KMT2A 1775/4885
US-20060029626-A1 Cosmetic composition CUTA, NGLY1, ARG1 ALOX15 686/4885MEN1 189/4885KMT2A 1769/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.