SCHEMBL7201805

SCHEMBL7201805

C=CCc1cccc2oc3ccccc3c12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IGF1R P08069 2/20 0.42
KDR P35968 2/20 0.42
GABRA1 P14867 1/20 0.42
GABRB2 P47870 1/20 0.42
AURKA O14965 1/20 0.42
DAPK3 O43293 1/20 0.42
MAP4K4 O95819 1/20 0.42
RET P07949 1/20 0.42
MET P08581 1/20 0.42
PIM1 P11309 1/20 0.42
LTK P29376 1/20 0.42
MAPK8 P45983 1/20 0.42
MAPK9 P45984 1/20 0.42
CDK8 P49336 1/20 0.42
CLK2 P49760 1/20 0.42
CDK9 P50750 1/20 0.42
CDK5 Q00535 1/20 0.42
ACVR1 Q04771 1/20 0.42
PTK2 Q05397 1/20 0.42
MAP4K2 Q12851 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9844965 0.81 MGAM (0.49) IGF1RKDRAURKADAPK3MAP4K4
SCHEMBL16500808 0.81 ALOX5 (0.50) IGF1RKDRGABRA1GABRB2AURKA
SCHEMBL754169 0.79 ALDH1A1 (0.43) IGF1RKDRMAOACYP3A4KDM4E
SCHEMBL2954355 0.77 MAOA (0.47) IGF1RKDRMAOACYP3A4KDM4E
SCHEMBL3268638 0.76 KDM4E (0.56) IGF1RKDRAURKADAPK3MAP4K4
SCHEMBL19802189 0.76 ALOX5 (0.44) IGF1RKDRMAOACYP3A4KDM4E
SCHEMBL9425618 0.76 MAOA (0.48) GABRA1GABRB2MAOACYP3A4KDM4E
SCHEMBL13201404 0.76 ALDH1A1 (0.43) IGF1RKDRMAOACYP3A4KDM4E
SCHEMBL7035976 0.76 ALDH1A1 (0.43) IGF1RKDRMAOACYP3A4KDM4E
SCHEMBL31619949 0.74 GABRA1 (0.56) IGF1RKDRGABRA1GABRB2AURKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117330681-A Fine separation method of crude oil and polycyclic aromatic hydrocarbons with different ring numbers in sedimentary organic matters based on chromatographic column 中国石油大学(北京) 2024-01-02 CN claimed
US-11125690-B2 Corrosion inhibitors and kinetic hydrate inhibitors CHAMPIONX USA INC. (US) 2021-09-21 US claimed
US-20200166458-A1 Corrosion Inhibitors and Kinetic Hydrate Inhibitors ECOLAB USA INC. (US) 2020-05-28 US claimed
CN-110372570-A A kind of amine derivant and its preparation method and application of fluorenes and carbazole 武汉尚赛光电科技有限公司 2019-10-25 CN claimed
EP-3256693-A1 CORROSION INHIBITORS AND KINETIC HYDRATE INHIBITORS Ecolab USA Inc. (US) 2017-12-20 EP claimed
CN-107311955-A A kind of spiro fluorene class organic electroluminescent compounds and its organic electroluminescence device 上海道亦化工科技有限公司 2017-11-03 CN claimed
CN-107266385-A A kind of fluorenes class organic electroluminescent compounds and its organic electroluminescence device 上海道亦化工科技有限公司 2017-10-20 CN claimed
CN-107163066-A A kind of spiral shell azole organic electroluminescent compounds and its organic electroluminescence device 上海道亦化工科技有限公司 2017-09-15 CN claimed
WO-2016130475-A1 CORROSION INHIBITORS AND KINETIC HYDRATE INHIBITORS ECOLAB USA INC. (US) 2016-08-18 WO claimed
US-20160231247-A1 Corrosion Inhibitors and Kinetic Hydrate Inhibitors ECOLAB USA INC. (US) 2016-08-11 US claimed
CN-117330681-A Fine separation method of crude oil and polycyclic aromatic hydrocarbons with different ring numbers in sedimentary organic matters based on chromatographic column 中国石油大学(北京) 2024-01-02 CN disclosed
US-11125690-B2 Corrosion inhibitors and kinetic hydrate inhibitors CHAMPIONX USA INC. (US) 2021-09-21 US disclosed
CN-106986835-B Compound for organic electric element, organic electric element using same, and electronic device using same 德山新勒克斯有限公司 2021-02-02 CN disclosed
US-10836723-B2 Method for synthesizing sodium 2,2,6,6-tetramethylpiperidides KOBELCO ECO-SOLUTIONS CO., LTD. (JP) 2020-11-17 US disclosed
US-20200166458-A1 Corrosion Inhibitors and Kinetic Hydrate Inhibitors ECOLAB USA INC. (US) 2020-05-28 US disclosed
EP-1140047-B1 ENDOCRINE THERAPY FOR BREAST CANCER: COMBINED TREATMENT WITH TAMOXIFEN PLUS ALKYL PCDFS TEXAS A & M UNIV SYS (US) 2003-10-29 EP disclosed
EP-1140047-A2 ENDOCRINE THERAPY FOR BREAST CANCER: COMBINED TREATMENT WITH TAMOXIFEN PLUS ALKYL PCDFS THE TEXAS A&M UNIVERSITY SYSTEM (US) 2001-10-10 EP disclosed
US-6136845-A ANTITUMOR AGENTS; MIXTURE CONTAINING POLYCHLORINATED DIBENZOFURAN THE TEXAS A&M UNIVERSITY SYSTEM (US) 2000-10-24 US disclosed
WO-2000037065-A2 ENDOCRINE THERAPY FOR BREAST CANCER: COMBINED TREATMENT WITH TAMOXIFEN PLUS ALKYL PCDFS THE TEXAS A & M UNIVERSITY SYSTEM (US) 2000-06-29 WO disclosed
US-5371248-A High temperature stability MOBIL OIL CORPORATION (US) 1994-12-06 US disclosed