Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 8/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4280485 | 0.82 | OPRM1 (0.57) | OPRM1OPRD1 | |
| SCHEMBL4120390 | 0.75 | ADRB2 (0.53) | CYP2C9TSHRCYP2D6CYP3A4OPRM1 | |
| SCHEMBL12781874 | 0.74 | MAPT (0.70) | SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL4287232 | 0.72 | SLC6A3 (0.39) | CYP2C9TSHRCYP2D6HIF1ASMN1; SMN2 | |
| SCHEMBL10760411 | 0.70 | OPRM1 (0.66) | OPRM1ALDH1A1OPRD1 | |
| SCHEMBL18793811 | 0.70 | OPRM1 (0.66) | OPRM1ALDH1A1MAPTOPRD1 | |
| SCHEMBL4283594 | 0.70 | SMN1; SMN2 (0.47) | TSHRCYP2D6OPRM1SMN1; SMN2 | |
| SCHEMBL14438077 | 0.69 | MAPT (0.74) | CYP2C9CYP2D6CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL6600563 | 0.69 | MAPT (0.62) | CYP2C9TSHRCYP2D6CYP3A4ITGB3 | |
| SCHEMBL4273032 | 0.69 | MAPK1 (0.46) | CYP2C9CYP2D6OPRM1CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090253669-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2009-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253669-A1 | Substituted Sulfonamide Compounds | SULT2A1, STS, SULT1A1 | CYP2C9 19/4885TSHR 3282/4885CYP2D6 48/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.