Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4280485 | 0.87 | OPRM1 (0.57) | OPRM1EPHX2LMNA | |
| SCHEMBL4273032 | 0.85 | MAPK1 (0.46) | SMN1; SMN2HTTOPRM1EPHX2LMNA | |
| SCHEMBL4120887 | 0.74 | SLC6A9 (0.39) | SMN1; SMN2OPRM1LMNASLC6A9CYP2D6 | |
| SCHEMBL4276599 | 0.70 | CYP2C9 (0.49) | SMN1; SMN2OPRM1CYP2D6TSHR | |
| SCHEMBL802314 | 0.68 | CYP1A2 (0.54) | SMN1; SMN2HTTDRD3LMNAGAA | |
| SCHEMBL18390065 | 0.68 | HSD11B1 (0.64) | SMN1; SMN2HTTOPRM1EPHX2HSD11B1 | |
| SCHEMBL4280380 | 0.68 | OPRM1 (0.47) | SMN1; SMN2OPRM1LMNAKDM1AMAOB | |
| SCHEMBL25870846 | 0.67 | CYP1A2 (0.44) | OPRM1EPHX2CYP2D6TSHR | |
| SCHEMBL4548020 | 0.67 | POLB (0.69) | SMN1; SMN2HTTHSD11B1 | |
| SCHEMBL7838280 | 0.67 | BLM (0.71) | SMN1; SMN2HTTEPHX2HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090253669-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2009-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253669-A1 | Substituted Sulfonamide Compounds | SULT2A1, STS, SULT1A1 | SMN1; SMN2 824/4885HTT 2146/4885OPRM1 2798/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.