Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4279852 | 0.89 | TSHR (0.43) | ALDH1A1LMNAGABRA1GABRB2L3MBTL1 | |
| SCHEMBL3482236 | 0.87 | ALDH1A1 (0.35) | ALDH1A1LMNAHPGD | |
| SCHEMBL2961139 | 0.86 | ALDH1A1 (0.42) | ALDH1A1LMNAL3MBTL1MAPTMEN1 | |
| SCHEMBL5344850 | 0.85 | TSHR (0.41) | ALDH1A1GABRA1GABRB2L3MBTL1MAPT | |
| SCHEMBL4267871 | 0.84 | MAPT (0.40) | GABRA1GABRB2L3MBTL1MAPTNPSR1 | |
| SCHEMBL3482697 | 0.84 | LIPG (0.42) | L3MBTL1TSHRTDP1TP53CYP3A4 | |
| SCHEMBL3482332 | 0.79 | BCL2 (0.41) | ALDH1A1LMNAL3MBTL1MAPTHPGD | |
| SCHEMBL19809356 | 0.78 | ALDH1A1 (0.37) | ALDH1A1LMNAL3MBTL1MAPTMEN1 | |
| SCHEMBL426600 | 0.78 | ALDH1A1 (0.37) | ALDH1A1LMNAL3MBTL1MAPTNPSR1 | |
| SCHEMBL4274033 | 0.78 | GABRA1 (0.38) | ALDH1A1GABRA1GABRB2L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7604866-B2 | Comprising silica particles and at least one binder compound; good mechanical strength and abrasion resistance | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2009-10-20 | — | — | US | disclosed |
| US-20060269724-A1 | Comprising silica particles and at least one binder compound; good mechanical strength and abrasion resistance | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2006-11-30 | — | — | US | disclosed |