Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | F2R | P25116 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4281638 | 1.00 | ALDH1A1 (0.46) | ALDH1A1KDM4EMAPTKMT2AHPGD | |
| SCHEMBL10640211 | 0.89 | NFE2L2 (0.41) | ALDH1A1KDM4EMAPTKMT2AHPGD | |
| SCHEMBL10640215 | 0.89 | NFE2L2 (0.41) | ALDH1A1KDM4EMAPTKMT2AHPGD | |
| SCHEMBL6797172 | 0.85 | ALDH1A1 (0.47) | ALDH1A1KDM4EMAPTKMT2AHPGD | |
| SCHEMBL6797176 | 0.85 | ALDH1A1 (0.47) | ALDH1A1KDM4EMAPTKMT2AHPGD | |
| SCHEMBL5317693 | 0.83 | ALDH1A1 (0.48) | ALDH1A1KDM4EMAPTKMT2AHPGD | |
| SCHEMBL8050356 | 0.83 | ALDH1A1 (0.48) | ALDH1A1KDM4EMAPTKMT2AHPGD | |
| SCHEMBL69522 | 0.82 | ALDH1A1 (0.58) | ALDH1A1KDM4EMAPTKMT2AHPGD | |
| SCHEMBL10438847 | 0.82 | ALDH1A1 (0.58) | ALDH1A1KDM4EMAPTKMT2AHPGD | |
| SCHEMBL11554418 | 0.82 | NFE2L2 (0.54) | ALDH1A1KDM4EMAPTHPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110248971-B | Copolymer and optical film using the same | 东曹株式会社 | 2021-11-02 | — | — | CN | disclosed |
| US-7622462-B2 | Benzazepine derivatives and uses thereof | ROCHE PALO ALTO LLC (US) | 2009-11-24 | — | — | US | disclosed |
| US-20070281920-A1 | Benzazepine derivatives and uses thereof | ROCHE PALO ALTO LLC | 2007-12-06 | — | — | US | disclosed |
| US-5098901-A | Cardiovascular disorders | STERLING DRUG INC. (US) | 1992-03-24 | — | — | US | disclosed |
| US-3987176-A | COMPOSITION AND USE OF 3,4-DIHYDROPYRIDONES AS VASODILATORS AND ANTIHYPERTENSIVE AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-10-19 | — | — | US | disclosed |
| US-3981882-A | HYPOTENSIVE AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-09-21 | — | — | US | disclosed |
| US-3951990-A | CORONARY AGENTS, HYPOTENSIVE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-04-20 | — | — | US | disclosed |
| US-3951992-A | CORONARY, HYPOTENSIVE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-04-20 | — | — | US | disclosed |
| US-3951991-A | CORONARY AGENTS, HYPOTENSIVE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070281920-A1 | Benzazepine derivatives and uses thereof | TPH1, TPH2, HTR2B | ALDH1A1 348/4885KDM4E 879/4885MAPT 1035/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.