SCHEMBL4283437

SCHEMBL4283437

CC(C)(C)c1ccc(-c2ccccc2O)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.58
RAB9A P51151 4/20 0.58
KMT2A Q03164 3/20 0.58
MEN1 O00255 2/20 0.58
NR2F2 P24468 1/20 0.58
ALDH1A1 P00352 6/20 0.58
HSD17B10 Q99714 3/20 0.58
HPGD P15428 2/20 0.58
BCL2L1 Q07817 1/20 0.58
KDM4E B2RXH2 2/20 0.51
TRPV1 Q8NER1 1/20 0.49
LMNA P02545 2/20 0.48
TYR P14679 1/20 0.48
POLB P06746 2/20 0.46
TDP1 Q9NUW8 2/20 0.45
TSHR P16473 1/20 0.45
KDM1A O60341 1/20 0.44
ESR2 Q92731 1/20 0.44
HSD11B1 P28845 1/20 0.44
HSD17B3 P37058 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30504387 0.89 KMT2A (0.52) NPC1RAB9AKMT2AMEN1NR2F2
SCHEMBL344516 0.88 ALDH1A1 (0.58) NPC1RAB9AKMT2AMEN1NR2F2
SCHEMBL2416998 0.88 ALDH1A1 (0.58) NPC1RAB9AKMT2AMEN1NR2F2
SCHEMBL28026490 0.84 ALDH1A1 (0.49) NPC1RAB9AKMT2AMEN1NR2F2
SCHEMBL11067075 0.84 ALDH1A1 (0.59) NPC1RAB9AKMT2AMEN1NR2F2
SCHEMBL28357036 0.82 ALDH1A1 (0.47) NPC1RAB9AKMT2AMEN1NR2F2
SCHEMBL714236 0.82 ALDH1A1 (0.83) NPC1RAB9AALDH1A1HSD17B10HPGD
SCHEMBL29443997 0.82 ALDH1A1 (0.83) NPC1RAB9AALDH1A1HSD17B10HPGD
SCHEMBL28502695 0.82 ALDH1A1 (0.50) NPC1RAB9AKMT2AMEN1NR2F2
SCHEMBL29206155 0.81 EGFR (0.54) NPC1RAB9AKMT2AMEN1NR2F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110065804-A1 ELECTRODEPOSITED METALLIC FINISHES INCLUDING ANTIMICROBIAL AGENTS PAVCO INC. (US) 2011-03-17 US claimed
WO-2009120784-A2 ELECTRODEPOSITED METALLIC FINISHES INCLUDING ANTIMICROBIAL AGENTS PAVCO INC. (US) 2009-10-01 WO claimed
WO-2002050002-A1 NON-HALOGENATED PHENYL SUBSTITUTED PHENOLS, ANTIMICROBIAL COMPOSITIONS CONTAINING THE SAME, AND METHODS OF USING THE SAME WARNER-LAMBERT COMPANY LLC (US) 2002-06-27 WO claimed
US-11352364-B2 Phthalocyanine nanosphere, preparation method thereof, and color filter TCL CHINA STAR OPTOELECTRONICS TECHNOLOGY CO. LTD. (CN) 2022-06-07 US disclosed
CN-113881029-A Polysiloxane end-capped modified copolycarbonate and preparation method thereof 万华化学集团股份有限公司 2022-01-04 CN disclosed
US-20210163492-A1 PHTHALOCYANINE NANOSPHERE, PREPARATION METHOD THEREOF, AND COLOR FILTER TCL CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) 2021-06-03 US disclosed
CN-109180888-B Modified alkylphenol-acetaldehyde resin and preparation method thereof 山东阳谷华泰化工股份有限公司 2021-03-12 CN disclosed
US-20190257049-A1 Methods and Apparatus for Stabilization of Surfaces Polylast Systems, LLC 2019-08-22 US disclosed
US-10309070-B2 Methods and apparatus for stabilization of surfaces Polylast Systems, LLC (US) 2019-06-04 US disclosed
US-10202354-B2 Therapeutic compounds and uses thereof GENENTECH, INC. (US) 2019-02-12 US disclosed
US-9982143-B2 Methods and apparatus for stabilization of surfaces Polylast Systems, LLC (US) 2018-05-29 US disclosed
US-20050096452-A1 Polyarylene oxide and method of producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-05-05 US disclosed
US-20040267057-A1 Method for producing phenol condensate SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-12-30 US disclosed
US-20030207945-A1 Non-halogenated phenyl substituted phenols, antimicrobial compositions containing the same, and methods of using the same HARPER DAVID SCOTT (US) 2003-11-06 US disclosed
US-20020119106-A1 Non-halogenated phenyl substituted phenols, antimicrobial compositions containing the same, and methods of using the same HARPER DAVID SCOTT (US) 2002-08-29 US disclosed
CN-1088579-C Antiplaque oral composition COLGATE PALMOLIVE CO (US) 2002-08-07 CN disclosed
CN-1200025-A Antiplaque oral composition COLGATE PALMOLIVE CO (US) 1998-11-25 CN disclosed
EP-0852486-A2 ANTIPLAQUE ORAL COMPOSITION Colgate-Palmolive Company (US) 1998-07-15 EP disclosed
US-5723500-A WATER INSOLUBLE, NONCATIONIC, ANTIBACTERIAL, STERICALLY HINDERED PHENOL; MOUTHWASHES, DENTIFRICES COLGATE-PALMOLIVE COMPANY (US) 1998-03-03 US disclosed
WO-1997010800-A2 ANTIPLAQUE ORAL COMPOSITION COLGATE-PALMOLIVE COMPANY (US) 1997-03-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030207945-A1 Non-halogenated phenyl substituted phenols, antimicrobial compositions containing the same, and methods of using the same TYR, CLPP, PTPN1 NPC1 460/4885RAB9A 3725/4885KMT2A 2835/4885
US-11352364-B2 Phthalocyanine nanosphere, preparation method thereof, and color filter IK, RB1, CRYAB NPC1 1003/4885RAB9A 2004/4885KMT2A 1082/4885
US-20210163492-A1 PHTHALOCYANINE NANOSPHERE, PREPARATION METHOD THEREOF, AND COLOR FILTER IK, RB1, CRYAB NPC1 1003/4885RAB9A 2004/4885KMT2A 1082/4885
US-20040267057-A1 Method for producing phenol condensate SOD1, MLX, XDH NPC1 1765/4885RAB9A 4120/4885KMT2A 1442/4885
US-20020119106-A1 Non-halogenated phenyl substituted phenols, antimicrobial compositions containing the same, and methods of using the same TYR, CLPP, PTPN1 NPC1 460/4885RAB9A 3725/4885KMT2A 2835/4885
US-10202354-B2 Therapeutic compounds and uses thereof KDM1B, KDM6B, KDM2B NPC1 1175/4885RAB9A 2849/4885KMT2A 29/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.