Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ACLY | P53396 | 3/20 | 0.46 |
| ▸ | USP36 | Q9P275 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | USP8 | P40818 | 1/20 | 0.45 |
| ▸ | UQCRB | P14927 | 2/20 | 0.43 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5318573 | 0.92 | SLC40A1 (0.49) | KMT2AMEN1RECQLGAAHTT | |
| SCHEMBL5272349 | 0.88 | MEN1 (0.47) | KMT2AMEN1MAPTRECQLGAA | |
| SCHEMBL5267179 | 0.87 | KMT2A (0.50) | KMT2AMEN1MAPTRECQLGAA | |
| SCHEMBL5265199 | 0.86 | GAA (0.47) | KMT2AMEN1MAPTRECQLGAA | |
| SCHEMBL5266751 | 0.85 | ALDH1A1 (0.46) | KMT2AMEN1HTTKDM4EALDH1A1 | |
| SCHEMBL5267213 | 0.85 | ALDH1A1 (0.45) | KMT2AMEN1MAPTHTTKDM4E | |
| SCHEMBL5270408 | 0.84 | LMNA (0.49) | MAPTGAAMAPK1HTTALDH1A1 | |
| SCHEMBL5269046 | 0.84 | KCNA5 (0.50) | KMT2AMEN1MAPTRECQLGAA | |
| SCHEMBL5269789 | 0.83 | MEN1 (0.51) | KMT2AMEN1MAPTGAAHSD11B1 | |
| SCHEMBL5269858 | 0.83 | KMT2A (0.45) | KMT2AMEN1MAPTGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156582-A1 | Pyrazole Compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-18 | — | — | US | disclosed |
| EP-1847531-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156582-A1 | Pyrazole Compound | GSK3B, GSK3A, GSKIP | KMT2A 871/4885MEN1 1910/4885MAPT 868/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.