Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5266751 | 0.88 | ALDH1A1 (0.46) | KDM4ELMNASMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL5267213 | 0.88 | ALDH1A1 (0.45) | KDM4ELMNAALDH1A1POLBL3MBTL1 | |
| SCHEMBL5318573 | 0.88 | SLC40A1 (0.49) | GAAKDM4ELMNATSHRSMN1; SMN2 | |
| SCHEMBL5270408 | 0.87 | LMNA (0.49) | GAAHSD17B10LMNATSHRSMN1; SMN2 | |
| SCHEMBL5271810 | 0.87 | KCNA5 (0.50) | GAAHSD17B10KDM4ELMNATSHR | |
| SCHEMBL5269858 | 0.86 | KMT2A (0.45) | GAAKDM4ELMNASMN1; SMN2CYP2C9 | |
| SCHEMBL4284633 | 0.86 | KMT2A (0.49) | GAAKDM4ELMNAALDH1A1USP2 | |
| SCHEMBL5271482 | 0.85 | MCL1 (0.42) | GAAHSD17B10KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL5268210 | 0.84 | SMN1; SMN2 (0.54) | GAAHSD17B10KDM4ELMNATSHR | |
| SCHEMBL5266716 | 0.82 | LMNA (0.69) | GAAHSD17B10KDM4ELMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847531-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-24 | — | — | EP | disclosed |